Case Report. Progressive Jaundice Due to Lymphangiosis Carcinomatosa of the Liver: CT Appearance

Tada, Hisashi; Morimoto, Michio; Shima, Toshihide; Hirana, Hirofumi; Nakagawa, Yoshihiro; Shimamoto, Kazuhiko; Nagano, N

doi:10.1097/00004728-199607000-00029

Cited by 15 publications

(4 citation statements)

References 7 publications

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“…Not all cholangiocarcinomas manifest with the typical imaging pattern, and various atypical patterns are frequently seen. Homogeneous hypervascular enhancement is an uncommon finding but may be seen in a well-differentiated tumor with abundant lymphangitic metastasis from the extrahepatic tumor (57). The latter finding can be distinguished from periductal cholangiocarcinoma on the basis of (a) the absence of ductal dilatation and (b) diffuse involvement of both sides of the liver.…”

Section: Mass-forming Typementioning

confidence: 99%

Varying Appearances of Cholangiocarcinoma: Radiologic-Pathologic Correlation

Chung¹,

Kim²,

Park³

et al. 2009

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Intrahepatic cholangiocarcinoma is the second most common primary hepatic tumor. Various risk factors have been reported for intrahepatic cholangiocarcinoma, and the radiologic and pathologic findings of this disease entity may differ depending on the underlying risk factors. Intrahepatic cholangiocarcinoma can be classified into three types on the basis of gross morphologic features: mass-forming (the most common), periductal infiltrating, and intraductal growth. At computed tomography (CT), mass-forming intrahepatic cholangiocarcinoma usually appears as a homogeneous low-attenuation mass with irregular peripheral enhancement and can be accompanied by capsular retraction, satellite nodules, and peripheral intrahepatic duct dilatation. Periductal infiltrating cholangiocarcinoma is characterized by growth along the dilated or narrowed bile duct without mass formation. At CT and magnetic resonance imaging, diffuse periductal thickening and increased enhancement can be seen with a dilated or irregularly narrowed intrahepatic duct. Intraductal cholangiocarcinoma may manifest with various imaging patterns, including diffuse and marked ductectasia either with or without a grossly visible papillary mass, an intraductal polypoid mass within localized ductal dilatation, intraductal castlike lesions within a mildly dilated duct, and a focal stricture-like lesion with mild proximal ductal dilatation. Awareness of the underlying risk factors and morphologic characteristics of intrahepatic cholangiocarcinoma is important for accurate diagnosis and for differentiation from other hepatic tumorous and nontumorous lesions.

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Section: Mass-forming Typementioning

confidence: 99%

Varying Appearances of Cholangiocarcinoma: Radiologic-Pathologic Correlation

Chung¹,

Kim²,

Park³

et al. 2009

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395

236

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“…Unlike primary hepatocyte tumors, intrahepatic biliary tumors often remain centrally hypoattenuating (with or without rim enhancement) relative to the liver parenchyma in the arterial and portal venous phases, enhancing most prominently in the delayed phase, a feature which reflects their desmoplastic nature (2). The degree of desmoplasia in an intrahepatic cholangiocarcinoma is not only distinctive, but also has prognostic implications (22)(23)(24). Specifically, intrahepatic cholangiocarcinomas that are hypovascular in the hepatic arterial phase are more likely to demonstrate lymphatic, perineural, and biliary invasion such that tumor hypervascularity may serve as an independent pre-operative prognostic factor for disease free survival (25).…”

Section: Computed Tomography (Ct)mentioning

confidence: 99%

Multimodality imaging of intrahepatic cholangiocarcinoma

Fábrega-Foster¹,

Ghasabeh²,

Pawlik³

et al. 2017

Hepatobiliary Surg. Nutr.

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Intrahepatic cholangiocarcinomas account for approximately 20% of cases of cholangiocarcinomas.Three growth patterns or morphologic subtypes exist, including mass-forming, periductal-infiltrating, and intraductal-growth subtypes. Knowledge of these morphologic subtypes and their radiologic appearance aids in timely diagnosis, a key to optimizing patient outcomes. The morphologic variability of intrahepatic cholangiocarcinomas has a direct impact on the diagnostic sensitivity and specificity of various diagnostic imaging modalities, including ultrasound (US), computed tomography (CT), magnetic resonance imaging (MRI)/magnetic resonance cholangiopancreatography (MRCP), and positron emission tomography (PET).The following review emphasizes optimal imaging technique for each of these modalities and reviews the imaging appearance of each morphologic subtype of intrahepatic cholangiocarcinoma.

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“…Neuroendocrine tumours are typically hyperattenuating. Periportal lymphangitic metastasis occurring at the hilum may mimic a cholangiocarcinoma, but they do not show ductal dilatation and involve both sides of the liver [117]. Lymphoepithelioma-like carcinomas are rare malignancies which are associated with Epstein-Barr virus infection.…”

Section: Tumoursmentioning

confidence: 99%

Klatskin-Like Lesions

Kumar

Marudanayagam

2012

HPB Surgery

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Hilar cholangiocarcinoma, also known as Klatskin tumour, is the commonest type of cholangiocarcinoma. It poses unique problems in the diagnosis and management because of its anatomical location. Curative surgery in the form of major hepatic resection entails significant morbidity. About 5–15% of specimens resected for presumed Klatskin tumour prove not to be cholangiocarcinomas. There are a number of inflammatory, infective, vascular, and other pathologies, which have overlapping clinical and radiological features with a Klatskin tumour, leading to misinterpretation. This paper aims to summarise the features of such Klatskin-like lesions that have been reported in surgical literature.

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Case Report. Progressive Jaundice Due to Lymphangiosis Carcinomatosa of the Liver: CT Appearance

Cited by 15 publications

References 7 publications

Varying Appearances of Cholangiocarcinoma: Radiologic-Pathologic Correlation

Varying Appearances of Cholangiocarcinoma: Radiologic-Pathologic Correlation

Multimodality imaging of intrahepatic cholangiocarcinoma

Klatskin-Like Lesions

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