Case Report. Pulmonary Alveolar Microlithiasis: High-Resolution CT and MR Findings

Hoshino, Hideaki; Inomata, Shin-Ichiroh; Kurokawa, Keizo; Morita, Yuji; Yoshida, Kazuhiro; Akiba, Hidenari; Abe, Shosaku

doi:10.1097/00004728-199803000-00016

Cited by 36 publications

(51 citation statements)

References 9 publications

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“…Later reports, 7,8 using high-resolution CT (HRCT) scan, suggested that this line was caused by subpleural cysts. Hoshino et al 1 demonstrated that the black pleural line on the chest radiograph corresponded to the fat dense layer between the ribs and calcified parenchyma, and also reported for the first time MRI findings in this case as diffuse calcific micronodules, characterized by an increased signal intensity on T 1 -weighted images, predominantly in the posterior lower zones. There are several reports about findings of PAM on conventional CT and HRCT.…”

Section: Felsonsupporting

confidence: 64%

Pulmonary Alveolar Microlithiasis: High-Resolution CT Scan

Abu-Ghazzeh¹

2000

Ann Saudi Med

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Section: Felsonsupporting

confidence: 64%

Pulmonary Alveolar Microlithiasis: High-Resolution CT Scan

Abu-Ghazzeh¹

2000

Ann Saudi Med

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“…Hos hi no et al de mons tra ted that the black ple u ral li ne on the chest ra di og raph cor res pon ded to the fat den se la yer bet we en the ribs and cal ci fied pa rench yma. 16 Ho we ver, we think this sug ges tion is not va lid for all PAM ca ses. We de tec ted black ple u ral li ne in chest X-ray of ca se 1 ha ving 5-6 mm subp le u ral cysts.…”

Section: Fi Gu Rementioning

confidence: 87%

“…Hi de a ki et al repor ted that trans lu cent zo nes ca u sed by subp le u ral cysts sho uld be cal led by anot her na me and sho uld be dis tin gu is hed from the li ne that Fel son ori gi nally men ti o ned. 17 The ad van ta ges of high-re so lu ti on CT in detec ting mi ni mal struc tu ral chan ges in the lung parench yma ha ve be en re por ted pre vi o usly. 18,19 High-re so lu ti on CT scans show that the re is a gradi ent of dis tri bu ti on of the cal ci fi ca ti ons in which lung ba ses, es pe ci ally pos te ri or are mo re in vol ved more than the midd le and up per lung zo nes.…”

Section: Fi Gu Rementioning

confidence: 99%

Pulmonary Alveolar Microlithiasis: Radiologic Findings of Eight Cases in Turkey

Tanrıkulu¹,

Dagli²,

Şenyiğit³

et al. 2010

Turkiye Klinikleri J Med Sci

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A AB BS S T TR RA AC CT T O Ob b j je ec c t ti i v ve e: : Pul mo nary al ve o lar mic ro lit hi a sis (PAM) is a ra re idi o pat hic di se a se cha rac te ri zed by pre sen ce of dif fu se in nu me rab le mi nu te cal cu li cal led mic ro liths The aim of this re port was to des cri be the ra di og rap hic fin dings of PAM with par ti cu lar at ten ti on to fe a tu res pro vi ded by chest X-ray and high resolution computerized tomography (HRCT). M Ma at te er ri ia al l a an nd d M Me et t h ho od ds s: : We diag no sed thre e in dex ca ses of PAM who ca me from the sa me vil la ge in 1996 . In 2005 we per for med a study inc lu ding 279 re si dents of that vil la ge by using mic ro film scre e ning to de ter mi ne undiagnosed ca ses. Fi ve ad di ti o nal ca ses of PAM we re de tec ted and un der went HRCT. HRCT and chest X-ray ima ges of eight ca ses we re as ses sed spe ci fi cally for pat terns, dis tri bu ti on, and pro fu si on of pul mo nary ab nor ma li ti es. R Re e s su ul lt ts s: : Of eight ca ses, four we re adults and four we re chil dren. Dif fuse typi cal mic ro cal ci fi ca ti ons we re de tec ted in chest X-ray in three ca ses whi le re ti cu lo no du lar pattern was seen in three ca ses and re ti cu lar pat tern in two ca ses. Fi ne mic ro cal ci fi ca ti on, pa rench ymal band and fiss su ral pro mi nen ce we re the most com mon fin dings on HRCT. Small subp le u ral cysts we re de tec ted in five ca ses but only ca se 1 sho wed black ple u ral li ne in chest X-ray. One ca se had small subp le u ral bul la e and bronc hi ec ta tic chan ges in both lo wer lo bes pre do mi nantly in the left lung in HRCT. C Co on nc c l lu u s si i o on n: : Re la ti ves of a pa ti ent with PAM ha ving re ti cu lar or reticulonodular pattern in chest X-ray must be investigated in de ta i l for PAM beca u se it can be the early sta ge of the di se a se. HRCT has a ma jor im por tan ce for the de tec ti on of the ra pid prog res si on. K Ke ey y W Wo or rd ds s: : Lung di se a ses; mass chest X-ray; tho rax Ö ÖZ ZE ET T A Am ma aç ç: : Pul mo ner al ve o ler mik ro li ti azis (PAM), mik ro lit ola rak ad lan dı rı lan dif fuz sa yı la mayan kü çük kal ku lus la rın var lı ğı ile ka rak te ri ze na dir gö rü len idi yo pa tik bir has ta lık tır. Bu ça lış manın ama cı PAM has ta lı ğı nın rad yo lo jik bul gu la rı nı düz ak ci ğer gra fi si ve yük sek re zo lüs yon lu ak ci ğer to mog ra fi si (YRBT) arac lı ğı ile be ra ber or ta ya koy mak tır. G Ge er re eç ç v ve e Y Yö ön nt te em ml le er r: : 1996 yı lın -da ay nı köy den baş vu ran üç has ta ya PAM ta nı sı koy duk. 2005 yı lın da bi lin me yen ol gu la rı araş tır -mak ama cıy la ay nı köy de ya şa yan 279 ki şi yi mik ro film ta ra ma tek ni ği kul la na rak araş tır dık. İla ve ten beş ki şiye PAM ta nı sı ko nul du ve YRBT çe kil di. Top lam se kiz has ta nın YRBT ve düz gra fi le ri özel -lik le pul mo ner anor mal lik le rin pa ter ni, da ğı lı mı ve tu tu lu mu açı sın dan de ğer len di ril di. B Bu ul l g gu u l la ar r: : Se kiz ol gu nun dör dü...

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“…Multiple pulmonary nodular calcifi cations on chest X-ray and CT are a pathognomonic fi nding of PAM, and diffuse and intense tracer uptake in both lungs on bone scintigraphy is widely known [2][3][4]. To the best of our knowledge, there have been no reports on FDG uptake by the lung in cases of PAM.…”

Section: Discussionmentioning

confidence: 99%

“…Although computed tomography (CT) and bone scintigraphic fi ndings of PAM have been reported earlier, the uptakes of 18 F-fl uorodeoxyglucose (FDG) in FDG-positron emission tomography (PET)/CT in lung are not yet known [2][3][4]. FDG-PET has come to be recognized as a useful tumor imaging technique on the basis of the elevated glucose metabolism in tumor cells.…”

Section: Introductionmentioning

confidence: 99%

FDG-PET/CT finding of high uptake in pulmonary alveolar microlithiasis

et al. 2007

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Pulmonary alveolar microlithiasis (PAM) is a rare lung disease characterized by progressive intra-alveolar calcification. We present a case of PAM with abnormal accumulation of 18F-fluorodeoxyglucose (FDG) in both lungs. A 55-year-old man was referred to our hospital for progressive dyspnea. He had been diagnosed with PAM 25 years earlier by transbronchial lung biopsy. High-resolution computed tomography revealed multiple dense calcifications with little aerated lung. Combined positron emission tomography and computed tomography using 18F-FDG (FDG-PET/CT) showed the abnormal accumulation of FDG in both lungs with a maximal standardized uptake value of 7.3. High FDG uptake was observed mainly in the lung regions showing sparing calcification. The patient died of respiratory failure a month later and an autopsy revealed no significant inflammatory changes in either lung. We suspect that the markedly enhanced pulmonary FDG uptake may have some relation to the pathophysiology of PAM.

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Case Report. Pulmonary Alveolar Microlithiasis: High-Resolution CT and MR Findings

Cited by 36 publications

References 9 publications

Pulmonary Alveolar Microlithiasis: High-Resolution CT Scan

Pulmonary Alveolar Microlithiasis: High-Resolution CT Scan

Pulmonary Alveolar Microlithiasis: Radiologic Findings of Eight Cases in Turkey

FDG-PET/CT finding of high uptake in pulmonary alveolar microlithiasis

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