Case Report: Relapsing, Bacteremic Klebsiella Pneumoniae Meningitis in an Aids Patient

Holder, Clinton; Halkias, Demetrios G.

doi:10.1097/00000441-198801000-00012

Cited by 6 publications

(3 citation statements)

References 27 publications

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“…Underlying co-morbidities included diabetes, alcoholism and chronic liver disease[ 1 - 4 ]. Outside Taiwan, cases of K. pneumoniae meningitis have occurred, predominantly in other parts of Asia [ 5 - 7 ] but also in Europe [ 8 - 11 ] and North America [ 12 - 14 ]. The rarity of these cases outside Asia raises the possibility of ethnicity or country of origin predisposing individuals to invasive disease[ 15 ].…”

Section: Discussionmentioning

confidence: 99%

Community-acquired Klebsiella pneumoniae meningitis in an alcoholic patient with an infected pancreatic pseudocyst; a case report and review of literature

et al. 2007

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We report a case of a 49-year-old male with a history of chronic alcoholism and evidence of a pancreatic pseudocyst on CT scanning. He presented with a 3-days history of fever, loss of appetite and upper abdominal pain. Blood cultures grew Klebsiella pneumoniae and he improved clinically with a seven-day course of intravenous co-amoxiclav and metronidazole. Two weeks later he was readmitted to hospital with impaired consciousness and septic shock, and died three days later in intensive care. Post mortem examination revealed bacterial meningitis and an infected pancreatic pseudocyst. Klebsiella pneumoniae was isolated from the pancreas and meninges.

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Section: Discussionmentioning

confidence: 99%

Community-acquired Klebsiella pneumoniae meningitis in an alcoholic patient with an infected pancreatic pseudocyst; a case report and review of literature

et al. 2007

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“…a e~u g i n o s a ,~~~ and K. pneurnoniae. 186 The first three patients were treated successfully, but the last two deserve comment. One of them, a patient with AIDS, was diagnosed with Pseudornonas meningitis and treated for a month with combination ceftazidime-t0bramy~in.j~~ Relapse occurred 2 weeks after completion of therapy and treatment was resumed with imipenem-cilastatin.…”

Section: Central Nervous System Infectionsmentioning

confidence: 98%

“…A common feature is a chronic, relapsing course with often unfavorable outcome when traditional antimicrobial therapy is administered. Extended courses of antibiotics and second-or third-line agents have often been 122,148, 154, 172, lE5, 186 Careful clinical monitoring and follow-up are recommended to detect treatment failures or relapses that may necessitate changes in antibiotic therapy.…”

Section: Other Bacterial Infectionsmentioning

confidence: 99%

Neglected Pathogens: Bacterial Infections in Persons With Human Immunodeficiency Virus Infection A Review of the Literature (First of Two Parts)

Fish,

Danziger

1993

Pharmacotherapy

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Bacterial infections, including those that cause infection in the healthy host as well as those that are more opportunistic, occur very commonly among persons infected with the human immunodeficiency virus (HIV). Bacterial infections are a direct result of the severe humoral and cellular immune defects found in these patients. Epidemiologic factors such as intravenous drug use and stage of HIV infection may also play important roles. Pulmonary, bloodstream, gastrointestinal, central nervous system, skin and soft tissue, and catheter‐related infections are common, as are endocarditis, prostatitis, and others. Frequently reported pathogens are common organisms such as Staphylococcus aureus, Haemophilus influenzae, Streptococcus pneumoniae, and enteric gram‐negative pathogens, as well as less typical ones such as Listeria monocytogenes and Nocardia sp. The frequency of infection is specific to organ system and pathogen, often being many times higher than in immunocompetent hosts. Prompt recognition and aggressive therapy are required to reduce morbidity and mortality due to these infections.

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Septicaemia in patients with AIDS

Shanson

1990

Transactions of the Royal Society of Tropical Medicine and Hygi

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During a 5 year period at St Stephen's hospital, London, septicaemia was detected in 66 patients with the acquired immune deficiency syndrome (AIDS) and in 13 other patients with non-AIDS-associated HIV infections. The most frequent pathogens in patients with AIDS were Mycobacterium avium-intracellulare, Streptococcus pneumoniae, Pseudomonas aeruginosa, Cryptococcus neoformans and staphylococci. A series of HIV-associated septicaemias reported from other centres in different countries has shown great variation in the pattern of aetiological agents observed, which may partly reflect differences in the local socio-economic condition, ethnic backgrounds, other predisposing factors, and blood culture techniques. Salmonella species were a prominent cause of septicaemia in several reports. Most centres have also reported an increasing problem with septicaemias associated with intravenous lines in patients receiving antiviral or other parenteral drug therapy.

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Case Report: Relapsing, Bacteremic Klebsiella Pneumoniae Meningitis in an Aids Patient

Cited by 6 publications

References 27 publications

Community-acquired Klebsiella pneumoniae meningitis in an alcoholic patient with an infected pancreatic pseudocyst; a case report and review of literature

Community-acquired Klebsiella pneumoniae meningitis in an alcoholic patient with an infected pancreatic pseudocyst; a case report and review of literature

Neglected Pathogens: Bacterial Infections in Persons With Human Immunodeficiency Virus Infection A Review of the Literature (First of Two Parts)

Septicaemia in patients with AIDS

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