2023
DOI: 10.3389/fonc.2023.1226202
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Case Report: Resolution of high grade anal squamous intraepithelial lesion with antibiotics proposes a new role for syphilitic infection in potentiation of HPV-associated ASCC

A. Ranabhotu,
N. Habibian,
B. Patel
et al.

Abstract: IntroductionHuman Papillomavirus (HPV) is the primary risk factor for the development of anal intraepithelial neoplasia (AIN) and is a leading risk factor for anogenital squamous cell carcinoma (ASCC). Despite common shared risk factors for both HPV and syphilis, co-infection is not well documented, and the role of syphilitic infection in HPV-associated AIN and ASCC potentiation is not defined.Case description/methodsA 72-year-old single male presented with complaints of mild rectal pain and intermittent recta… Show more

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