Case Report: Scrambler Therapy for the Treatment of Chronic Post-Mastectomy Pain (cPMP)

Abstract

Chronic post-mastectomy pain (cPMP), including post-lumpectomy pain, is common with no established ways of treatment. We treated three consecutive patients referred with cPMP with scrambler therapy (ST), a non-invasive electrical neurocutaneous stimulation. Treatment was given across the area of pain following the dermatomes for 45 minutes daily, for several consecutive days until relief, and then was repeated as needed. The ST MC5A device synthesizes 16 different waveforms that resemble action potentials, delivered to the surface receptors of the c-fibers, to send “non-pain” information along the damaged pathways to reduce central sensitization. All three had marked (over 75%) and sustained (months) reduction of allodynia, hyperalgesia, and pain. All reported marked improvements in their quality of life and normal function. One woman was able to stop chronic opioid use. No side effects were observed.Scrambler therapy is a promising way to relieve cancer and other types of neuropathic pain, and may be helpful in cPMP. Further prospective trials are warranted.

Scrambler therapy improves pain in neuromyelitis optica

“…11 This neuromodulatory therapy has been investigated for the treatment of persistent peripheral neuropathic pain, largely in open-label observational trials, in several conditions including chemotherapy-induced neuropathy, postherpetic neuralgia, and postsurgical neuropathic pain with promising results. [11][12][13][14][15][16][17] Patients report sustained relief after undergoing daily treatment sessions for 10 consecutive weekdays. 11 Anecdotal evidence supports Scrambler therapy for use in patients with persistent central neuropathic pain, 18,19 but no rigorous studies have systematically tested the benefit or sustainability of Scrambler vs a placebo treatment.…”

Perfil epidemiológico de mulheres mastectomizadas em um serviço de referência localizado no Vale do Taquari/RS

“…Portanto, o impacto estético e mudança da rotina diária pode causar uma diminuição na qualidade de vida principalmente nos primeiros meses. 5,6,[22][23] Estudo que utilizou o questionário SF-36 apontou que mulheres que realizaram a cirurgia de quadrantectomia e não necessitaram de reconstrução mamária possuem os melhores escores médios em todos os domínios e, portanto, têm melhor qualidade de vida (QV), seguidas do grupo de mastectomizadas que fizeram reconstrução. O grupo de mulheres mastectomizadas que não fizeram a reconstrução tem um nível muito baixo de QV, seguido pelo grupo das mulheres que realizaram a quadrantectomia e também não fizeram a reconstrução.…”

Effects of scrambler therapy on pain and depression of patients with chronic low back pain: case study

“…Additionally, he read a full explanation of the study’s purpose and methods, and consented to this experiment. Investigational Review Board approval is not required if one or fewer cases are reported 7 ) . The study adhered to the principles of the Declaration of Helsinki.…”