Case Report: Survival of A Coronavirus Disease-2019 (Covid-19) Patient with Acute Respiratory Distress Syndrome (ARDS) in Dr. Soetomo Hospital, Surabaya, Indonesia

Abstract

An outbreak of coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that began in Wuhan, China has spread rapidly in multiple countries of the world and has become a pandemic. Currently, there is no vaccine or specific antiviral for COVID-19. A study reported 7.3% of critical patients admitted to ICU, 71% of them required mechanical ventilation, and 38.5% of them were survived. Herein, we reported a 54 year old man with Acute Respiratory Distress Syndrome (ARDS) of COVID-19 who survived the disease. Real-time reverse transcriptase-polymerase chain reaction (RT-PCR) assay of nasopharyngeal and oropharingeal swabs were positive for SARS-CoV-2. Diagnosis of ARDS was also according to clinical symptoms, laboratory, chest radiograph, and chest CT scan. Alcaligenes faecalis and Candida albicans were also identified from sputum culture. Treatment for this patient was causal and supportive therapy, including antibiotic, antiviral, and antifungal therapy according to the culture results, fluid resuscitation, and oxygen supply from the mechanical ventilator. This patient was survived and discharged on hospital day-29. A fibrosis in parenchyma pulmonary and sensory peripheral neuropathy occurred after survived from ARDS. Monitoring of clinical, laboratory, and chest radiograph were continued after the patient discharged from the hospital. This case highlights the importance of early diagnosis and effective treatment to the care of COVID-19 patient.

Association between chest X-ray score and clinical outcome in COVID-19 patients: A study on modified radiographic assessment of lung edema score (mRALE) in Indonesia

“…Radiological assessments play a crucial role in identifying and evaluating the severity of the disease, enabling the anticipation of clinical outcomes for COVID-19 patients [3]. A computed tomography (CT) scan has been recognized as the most effective modality for early disease detection and severity assessment due to its high sensitivity [2,[4][5][6].…”

Retinal Vein Occlusion Amongst People Vaccinated by mRNA- and Viral Vector- COVID-19 Vaccines: A Systematic Review

“…Anti-VEGF was a trending therapy in RVO with a total of 32 cases (41.02%). It is also considered to be a great therapy because of the great outcome we identified in this study, with 12 cases having improved outcomes after the treatment [case # 6,7,16,26,[28][29][30][31][32][33][34]69]. 28,35,44,46,47,53 In this review, more patients (52.00%) were vaccinated with the mRNA vaccine, even though viral vector vaccines were approved in more countries.…”

“…4 Some cases are mild and usually self-limiting, and some cases are asymptomatic. 4,6,7 However, many patients with comorbidities suffer from more severe symptoms, such as acute respiratory distress syndrome (ARDS), septic shock, or even multiple-organ failure. 4,7,8 SARS-CoV-2 is very contagious.…”

“…4,6,7 However, many patients with comorbidities suffer from more severe symptoms, such as acute respiratory distress syndrome (ARDS), septic shock, or even multiple-organ failure. 4,7,8 SARS-CoV-2 is very contagious. It is transmissible by inhalation or contact with droplets that contain the virus.…”

Tapak Liman (Elephantopus scaber L.) Leaves Ethanol Extract Improves the Production of IL-6 and IL-17 Cytokines in Mice with Bleomycin-induced Pulmonary Fibrosis

“…In contrast, pulmonary fibrosis in Indonesia is known to be part of acute respiratory distress syndrome (ARDS). The latest data indicates that 20% of patients with ARDS cases can develop progressive pulmonary fibrosis [7].…”