Case Report: Total Hip Replacement in a 12-Year-Old Girl with Protrusio Acetabuli and Disabling Joint Degeneration, Secondary to Femoral Head Idiopathic Chondrolysis—Six-Year Follow-Up

Megremis, Panos; Megremis, Orestis; Margariti, Rodanthi

doi:10.1007/s42399-020-00697-z

Cited by 3 publications

(3 citation statements)

References 18 publications

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“…More speci cally, we had 46 cases/ hips (17 studies) where MRI was reviewed at least once. However, there were 14 follow-up MRI reviews from 8 studies among these cases (6-8, 10,12,[25][26][27]. Two studies added a second follow-up review in one case each (8,25).…”

Section: Demographic Outcomesmentioning

confidence: 99%

“…We had 14 follow-up MRI reviews from 8 studies among 46 cases (6-8, 10,12,[25][26][27]. The median time to follow-up MRI in these hips was 12.5 (IQR 3.75-19.5) months (6 studies).…”

Section: Outcomes Of Follow-up Mri Reviewsmentioning

confidence: 99%

“…Recently pharmacological interventions and arthroscopic treatment have been reported with variable success in ICH (7)(8)(9)(10)(11). A study described total hip arthroplasty (THA) in adolescent ICH (12). We aimed to review the MRI characteristics and treatment options for ICH in children.…”

Section: Introductionmentioning

confidence: 99%

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MRI features and treatment options for Idiopathic Chondrolysis of the Hip (ICH) in children. Outcomes of a systematic review.

Nema

Ramasubramani

Austine

et al. 2022

Preprint

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Background: The purpose of this paper is to review the MRI features and treatment for idiopathic chondrolysis of the hip (ICH) in patients aged 18 years or less. Methods: We included studies published in English up to August 2021. We accessed major electronic bibliographic databases on ICH that described MRI features, treatment, or both. We used the Joanna Briggs Institute (JBI) Critical appraisal checklist for case reports for Risk of bias assessment.Results: We pooled 136 hips (125 participants) from 35 studies with 11.6 ± 3.4 years mean age. We had 46, 8, and 106 hips to assess ICH's MRI, pharmacological, and operative interventions. Geometric marrow edema (GME) (P < 0.01), diffuse marrow edema (DME) (P < 0.05), diffuse cartilage loss (DCL) (P < 0.05), and joint effusion (P < 0.05), were significantly associated with time in first MRI reviews. GME (P < 0.01) and focal cartilage loss (FCL) (P < 0.01) decreased significantly between two MRI reviews at median time of 1.75 (IQR 0.93-4.25) and 12.5 (IQR 3.75-19.5) months. Diffuse cartilage loss (P < 0.01) and degenerative changes (P < 0.01) increased significantly between the two MRI reviews. Etanercept, Methotrexate, and Botulinum Neurotoxin A drugs were used by 3, 3, and 1 report to treat ICH. Capsulectomies, total hip arthroplasty, arthrodiastasis, arthrodesis, arthroscopy operations treated 45, 18, 5, 5, and 2 hips. Discussion: GME may be the most specific and early MRI feature in diagnosing ICH. GME and DME show an inverse relationship over time. So, it is with FCL and DCL. Despite reports on the efficacy of biologics, immunomodulators, and operations, early and late ICH management remains controversial due to poor quality studies.

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Section: Demographic Outcomesmentioning

confidence: 99%

“…We had 14 follow-up MRI reviews from 8 studies among 46 cases (6-8, 10,12,[25][26][27]. The median time to follow-up MRI in these hips was 12.5 (IQR 3.75-19.5) months (6 studies).…”

Section: Outcomes Of Follow-up Mri Reviewsmentioning

confidence: 99%