2015
DOI: 10.1038/sj.bdj.2015.933
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Case reports: Palatal mucosal necrosis after administration of a palatal infiltration

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Cited by 5 publications
(4 citation statements)
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“…As the damage of the greater palatal and nasopalatine nerve and blood supply was excluded, the palatal mucosa necrosis that appeared after implant extraction could be explained by the contraction of smooth muscle within the arterial wall during the neurovascular bundle constriction that leads to transient ischemia of structures and tissue necrosis [28]. However, the definite terms of the necrosis manifestation are still unclear.…”
Section: Discussionmentioning
confidence: 99%
“…As the damage of the greater palatal and nasopalatine nerve and blood supply was excluded, the palatal mucosa necrosis that appeared after implant extraction could be explained by the contraction of smooth muscle within the arterial wall during the neurovascular bundle constriction that leads to transient ischemia of structures and tissue necrosis [28]. However, the definite terms of the necrosis manifestation are still unclear.…”
Section: Discussionmentioning
confidence: 99%
“…Thus, epinephrine contained in many local anaesthetic agents may be a possible cause of ischaemia and secondary necrosis. [ 6 ]…”
Section: Discussionmentioning
confidence: 99%
“…The contraction of smooth muscle within the arterial wall during vasoconstriction may lead to transient ischemia of structures distally to the injection site leading to tissue necrosis. [ 7 ] Furthermore, vasoconstrictors in local anesthetics reduce the oxygen supply to the injected tissue and promote the buildup of acidic by-products of metabolism. In addition, local anesthetic solutions with vasoconstrictors are adjusted to a lower pH to preserve the vasoconstrictors which however accentuate tissue acidity.…”
Section: Discussionmentioning
confidence: 99%
“…To minimize the incidence of palatal lesions following the administration of LA, the following precautions are recommended:[ 7 ]…”
Section: Discussionmentioning
confidence: 99%