2020
DOI: 10.21203/rs.3.rs-35104/v1
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Caspase 4 Overexpression in Clear Cell Renal Cell Carcinoma and Its Prognostic Role

Abstract: Background: Caspase 4 (CASP4) dysregulation is related to the occurrence, development, and outcome of many malignant tumors, but its role in clear cell renal cell carcinoma (ccRCC) is unclear. This study was conducted to investigate the expression level of CASP4 in tumor tissues and its relationship with clinical prognosis of patients with ccRCC. Methods: First, the Oncomine and The Cancer Genome Atlas databases were used to determine CASP4 mRNA expression in ccRCC and its association with ccRCC prognosis. We … Show more

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