“…Some species of Caesalpinia genus such as C. bonduc, C. sappan have been commonly used in traditional medicine for a long time as functional food, supporting the prevention of some diseases such as rheumatism, back pain, antipyretic around the world [1,4,5]. Previous studies showed that the chemical constituents of the Caesalpinia genus contained a diversity of secondary metabolites such as lignans, _______ https://doi.org/10.25073/2588-1140/vnunst.5500 flavonoids, and terpenes [3,6,7]. They have a variety of characteristic biological activities like anti-inflammatory, anti-oxidant, anti-bacterial, and anti-diabetes [3,4,[6][7][8].…”