Cassia occidentalis L.: A review on its ethnobotany, phytochemical and pharmacological profile

Sub-acute Toxicity of Aqueous Extracts of Tephrosia vogelii, Vernonia amygdalina and Senna occidentalis in Rats

“…The geographical location, season, soil type, climate differences, agronomic practices, plant part and age affect the concentration of phytochemicals, usually leading to differences in bioactivity and toxicity [7,16,18]. Using proteomics, metabolomics and transcriptomics in recent advances to determine nephrotoxic, genotoxic and teratogenic effects of natural plant products has been recommended [34].…”

“…However, qualitative phytochemistry (results not presented here) showed both anthracenosides and anthocyanosides in the aqueous extract of TV and VA. The seeds of SO are reportedly toxic to many vertebrates and the unnamed toxic albumin is incriminated [18]. This study however, considered only the leaf extracts and thus some of these toxic rinciples may have been in limited amounts (no specific tests done presently).…”

“…The leaf extracts of VA are used to treat malaria, gastrointestinal ailments [13][14][15][16] and reducing blood sugar levels in dogs [17]. Senna occidentalis Linn (Family Caesalpiniaceae; synonym Cassia occidentalis L.; ILDIS id 1087), is a 0.8-1.5 m tall, smooth leafed perennial plant important in traditional medicine in the tropics [10,18]. It has good antimicrobial, anti-mutagenic, anti-inflammatory, anti-diabetic and anti-malarial activity [18][19][20].…”

“…Senna occidentalis Linn (Family Caesalpiniaceae; synonym Cassia occidentalis L.; ILDIS id 1087), is a 0.8-1.5 m tall, smooth leafed perennial plant important in traditional medicine in the tropics [10,18]. It has good antimicrobial, anti-mutagenic, anti-inflammatory, anti-diabetic and anti-malarial activity [18][19][20]. Acute toxicity studies of leaves of TV [21], VA [15,22,23] and seeds of SO [24][25][26][27][28] have been studied in different animals.…”

Molecular Docking Studies of Phytoconstituents Identified in Crocus sativus, Curcuma longa, Cassia occidentalis and Moringa oleifera on Thymidylate Synthase and ndash; An Enzyme Target for Anti-Cancer Activity

“…Cassia occidentalis L. is an annual or perennial ayurvedic plant which is used in several traditional medicines to cure various diseases. This weed has been known to possess antibacterial, antifungal, antidiabetic, anti-inflammatory, anticancerous, antimutagenic and hepatoprotective activity (Yadav et al, 2010). Moringa oleifera Lam (Moringaceae) is a highly valued plant, distributed in many countries of the tropics and subtropics.…”