Castleman's disease of the retropharynx: A benign tumor in a 12-year-old girl

Dangoor, Eric; Elidan, Josef; Gomori, John M.; Dano, Isaac

doi:10.1016/s0196-0709(98)90087-4

Cited by 7 publications

(8 citation statements)

References 7 publications

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“…%10'dan daha az bir oranda hastalık pelviste ve diğer organlara yerleşir (1,9). Bizim hastamızda olduğu gibi parafarengeal yerleşim ise çok nadir olup, literatürde şimdiye kadar toplam beş pediatrik hastada parafarengeal yerleşimli CH bildirilmiştir (10)(11)(12)(13)(14).…”

Section: Discussionunclassified

Pediatric Parapharyngeal Castleman's Disease: A Case Report

Erbey¹,

Bayram²,

Tuncer³

et al. 2009

TUTFD

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Castleman's disease is a rare lymphoproliferative disorder of unknown aetiology. It has two clinical expressions. The localized form, which usually presents as a slow growing mass and the multicentric form, where tumoural involvement is multilocated. Mediastinal involvement is the most common location of presentation. Parapharyngeal involvement is very rare and, to our knowledge, five pediatric parapharyngeal Castleman's disease have been reported. We describe the case of a 14-year-old female child who was diagnosed as having parapharyngeal Castleman's disease.

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Section: Discussionunclassified

Pediatric Parapharyngeal Castleman's Disease: A Case Report

Erbey¹,

Bayram²,

Tuncer³

et al. 2009

TUTFD

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“…3,8 After resection of the tumor, symptoms and laboratory data improved in some cases. 20,21 Radiotherapy, 22 chemotherapy, 23 steroid therapy, and/or immunosuppressive agents have been applied in refractory cases, resulting in the improvement of clinical symptoms. However, improvement of C-reactive protein and g-globulin levels has been demonstrated rarely.…”

Section: Discussionmentioning

confidence: 99%

Castleman's Disease of the Rectum: Report of a Case

Hata¹,

Ikeda²,

Ikenaga³

et al. 2007

Diseases of the Colon &Amp; Rectum

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Gastrointestinal Castleman's disease is very rare. We report the case of a 52-year-old patient with asymptomatic rectal polyp, which was diagnosed as Castleman's disease. The rectal polyp was identified during preoperative workup of gastric adenocarcinoma. The rectal polyp was 4-cm long with a short, thick stalk. Pathologic examination of the resected polyp showed lymph follicle hyperplasia with remarkable lymphocyte and plasma cell infiltration in the submucosal area, consistent with plasma cell type of Castleman's disease. This is the first report of Castleman's disease of the rectum concomitant with gastric adenocarcinoma. A literature review of Castleman's disease identified only five cases of gastrointestinal Castleman's disease, and all five cases were of the hyaline vascular type. A high index of suspicion of this disease is important for preoperative diagnosis.

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“…3,5 In the head and neck, lesions are often closely associated with the sternocleidomastoid muscle, although involvement of the larynx, submandibular region, parapharyngeal region, and retropharynx has been reported. 6,7 Histologically, the hyaline vascular type of CD is characterized by the proliferation of morphologically distinct lymphoid follicles that obscure underlying nodal architecture. The follicles consist of germinal centers surrounded by a cuff of small mature lymphocytes arranged in concentric (onionskin) layers with radially arranged capillaries that penetrate the germinal centers.…”

Section: Diagnosis Pathology Quiz Casementioning

confidence: 99%

“…Preoperative embolization has been advocated to facilitate surgical excision and to decrease intraoperative bleeding. [6][7][8] The optimal therapeutic approach to CD has not been completely elucidated. Most reports describing surgical resection for unicentric CD, both the hyaline vascular type and the plasma cell type, have demonstrated that complete resection is curative.…”

Section: Diagnosis Pathology Quiz Casementioning

confidence: 99%

Pathology Quiz Case

Zim

Doherty²,

Ma³

et al. 2001

Arch Otolaryngol Head Neck Surg

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A 40-YEAR-OLD otherwise-healthy white man presented with a 14-year history of a painless mass in the left side of his neck. He denied dysphagia, odynophagia, weight changes, voice changes, fever, chills, nausea, and vomiting. He did not smoke cigarettes or drink alcohol. Physical examination revealed no abnormalities except for a 6ϫ5-cm nontender, firm, mobile mass that was palpable in the left posterior triangle of the neck.The findings of fine-needle aspiration biopsy were nondiagnostic. A chest x-ray film was normal. A computed tomographic scan revealed a large enhancing mass in the left posterior cervical space (Figure 1). The wellencapsulated mass was subsequently excised in the operating room through a transverse incision in the posterior triangle of the neck. The histological findings are shown in Figure 2 and Figure 3.

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Castleman's disease of the retropharynx: A benign tumor in a 12-year-old girl

Cited by 7 publications

References 7 publications

Pediatric Parapharyngeal Castleman's Disease: A Case Report

Pediatric Parapharyngeal Castleman's Disease: A Case Report

Castleman's Disease of the Rectum: Report of a Case

Pathology Quiz Case

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