In this paper, the contributions to the Macroheterocera fauna of Mutki district of Bitlis Province (East Anatolia) are presented. The samples collected between 2010-2012 are evaluated. All given 192 species are recorded for the first time from moth fauna of Mutki and likewise 85 species are recorded for the first time from moth fauna of Bitlis. Additionally, adult and male genitalia of Eupithecia gemellata Herrich-Schäffer, 1861 and Chondrostega palaestrana Staudinger, 1892 are illustrated and distribution of them are given.