Catalpol promotes articular cartilage repair by enhancing the recruitment of endogenous mesenchymal stem cells
Congzi Wu,
Zhenyu Shi,
Qinwen Ge
et al.
Abstract:Articular cartilage defect is challenged by insufficient regenerative ability of cartilage. Catalpol (CA), the primary active component of Rehmanniae Radix, could exert protective effects against various diseases. However, the impact of CA on the treatment of articular cartilage injuries is still unclear. In this study, full‐thickness articular cartilage defect was induced in a mouse model via surgery. The animals were intraperitoneally injected with CA for 4 or 8 weeks. According to the results of macroscopic… Show more
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