Catalysis and mechanistic study of Ru(III) and Os(VIII) on the oxidation of taurine by BAT in acid and alkaline media: a kinetic modeling

Suresha, N.; Raj, Kalyan; Malini, S.

doi:10.1080/24701556.2020.1799394

Cited by 2 publications

(3 citation statements)

References 23 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Suresha et al investigated the kinetics behind Ru(III)- and Os(VIII)-catalysed taurine (TAU) oxidation at 313 K using bromamine-T in both HCl and NaOH media (Scheme 83 ). 111 The rate laws were deduced and found to be rate = k [BAT] t [TAU] 0 [Ru(III)] 0.95 [H + ] –0.67 in acidic medium and rate = k [BAT] t [Os(VIII)] 0.89 [ – OH] –0.53 in basic medium. It was observed that the rate of the reaction in both cases remained unaffected by the addition of halide ions and p -toluenesulfonamide.…”

Section: Organic Transformations Using Bromamine-tmentioning

confidence: 99%

“…Scheme 82 Oxidative decolorization of methyl red with chloramine-T and bromamine-T Suresha et al investigated the kinetics behind Ru(III) and Os(VIII) catalysed Taurine oxidation at 313 K using bromamine-T in both HCl and NaOH media (Scheme 83) 111. The rate laws were deduced and found to be rate= k[BAT]t[TAU] 0 [Ru(III)] 0.95 [H + ] -0 67.…”

mentioning

confidence: 99%

“…In contrast to CAT, the oxidation of MR with BAT proved to be about four times faster. 111 The rate laws were deduced and found to be rate = k[BAT] t [TAU] 0 [Ru(III)] 0.95 [H + ] -0.67 in acidic medium and rate = k[BAT] t [Os(VIII)] 0.89 [ -OH] -0.53 in basic medium. It was observed that the rate of the reaction in both cases remained unaffected by the addition of halide ions and p-toluenesulfonamide.…”

mentioning

confidence: 99%

See 2 more Smart Citations

Bromamine-T (TsNBrNa): A Biologically Significant, Versatile Bromo-Organic Reagent

Kashyap¹,

Phukan²

2023

Synlett

View full text Add to dashboard Cite

Bromamine-T (BAT) is a distinguished member of a special class of compounds called organic haloamines, possessing oxidising properties. It can act as the source of halonium ions, hypohalite species, and N-anions, along with the display of basic as well as nucleophilic properties. Bromamine-T finds wide application as an efficient reagent for various organic transformations such as aminobromination, amination, oxidation etc., under mild conditions with minimum toxicity. Moreover, due to its immense biological significance, this reagent is piquing the interest of numerous researchers.

show abstract

Section: Organic Transformations Using Bromamine-tmentioning

confidence: 99%

mentioning

confidence: 99%

mentioning

confidence: 99%

See 1 more Smart Citation

Bromamine-T (TsNBrNa): A Biologically Significant, Versatile Bromo-Organic Reagent

Kashyap¹,

Phukan²

2023

Synlett

View full text Add to dashboard Cite

show abstract

Chloramine-T-induced oxidation of Rizatriptan Benzoate: An integral chemical and spectroscopic study of products, mechanisms and kinetics

Malini,

Raj,

Kumari

et al. 2023

Open Chemistry

View full text Add to dashboard Cite

Oxidation is a prominent degradation route of biological molecules that produces a wide variety of degradation products through complex mechanisms and hence qualifies to be a vital pharmaceutical process. This article presents the kinetic and spectral study of the oxidation of an antimigraine drug rizatriptan benzoate (RTB) in an acid medium with the aid of a mild biocidal oxidant N-chloro-p-toluenesulfonamide, referred to as chloramine-T (CAT). The kinetic experimental studies reported here, such as fractional order dependency on RTB, pseudo-first-order dependency on CAT, negative fractional order dependency on the acid medium, independent of the rate on the ionic concentration and increasing rate with increasing dielectric constant, have led to the evaluation of stoichiometry, thermodynamic properties, and derivation of a rate equation. Effective interpretation of UV–Vis, IR, 1H and 13C NMR investigation was performed to identify and confirm the identity of the oxidation products and discuss the involved plausible mechanism. This study provides an extended insight into the products of oxidation formed during the metabolism of RTB.

show abstract

Catalysis and mechanistic study of Ru(III) and Os(VIII) on the oxidation of taurine by BAT in acid and alkaline media: a kinetic modeling

Cited by 2 publications

References 23 publications

Bromamine-T (TsNBrNa): A Biologically Significant, Versatile Bromo-Organic Reagent

Bromamine-T (TsNBrNa): A Biologically Significant, Versatile Bromo-Organic Reagent

Chloramine-T-induced oxidation of Rizatriptan Benzoate: An integral chemical and spectroscopic study of products, mechanisms and kinetics

Contact Info

Product

Resources

About