Catalyst‐ and Light‐free S−H Insertion between Phosphorodithioic Acids and Diazo Compounds: Rapid Access to Dialkylphosphorodithioates

Abstract

A catalyst-and light-free SÀ H insertion of phosphorodithioic acids with diazo compounds has been developed, in which phosphorodithioic acid acts not only as an acid promoter but also as a nucleophile. This protocol features fast reaction rate, broad substrate scope, mild conditions, and simple operation, providing a cost-effective and general approach to diverse phosphorodithioates.

O–H Insertion of Hydrogenphosphate Derivatives and α-Diazo Compounds

“…Based on the previous reports − ,, and the results presented in our study, a possible mechanism was proposed (Scheme ). First, the diazo compound 2 would be protonated by hydrogenphosphate derivative 1 in the form of dipole, generating the diazonium ion pair I .…”