“…2, 152.8, 150.5, 146.4, 142.9, 142.3, 138.0, 137.5, 135.1, 133.3, 131.5, 130.2, 129.6, 129.4, 129.0, 128.8, 128.7, 128.5, 127.8, 127.6, 126.6. MS (EI, 70 eV) m/z (%): 103 (14), 255 43) 359 (100[M] + . -2-yl)-[1,1'-biphenyl]-4-carbonitrile (12): Following general Procedure B using 2-phenylpyrazine (234 mg, 1.5 mmol) and 4bromobenzonitrile (182 mg, 1 mmol), the residue was purified by flash chromatography on aluminium oxide (Heptane-EtOAc, 90-10) to afford the desired compound 12 (182 mg, 71 %) as a pale yellow solid (Mp = 142-144°C): 1 H NMR (400 MHz, CDCl 3 ) δ 8.54 (s, 1H), 8.41 (d, J = 2.3 Hz, 1H), 8.24 (s, 1H), 7.71 (dd, J = 5.6, 3.4 Hz, 1H), 7.60-7.52 (m, 4H), 7.45 (dd, J = 5.6, 3.4 Hz, 1H), 7.24 (d, J = 8.2 Hz, 2H).…”