Catalyst-free three-component synthesis of hydroxyalkyltriazolylmethylidene barbiturates

Демина, М. М.; Медведева, А. С.; Vu, Tran D.; Ларина, Л. И.; Mitroshina, I. V.; Shemyakina, Olesya A.

doi:10.1016/j.mencom.2019.11.017

Cited by 2 publications

(1 citation statement)

References 52 publications

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“…The stereochemical behavior and annular ptototropic tautomerism of 4-substituted 1,2,3-triazoles was studied by multinuclear 1 H, 13 C, 15 N and 29 Si NMR spectroscopy and quantum chemistry [113,114,117,118].…”

Section: Functional 123-triazole Derivativesmentioning

confidence: 99%

The Structure of Biologically Active Functionalized Azoles: NMR Spectroscopy and Quantum Chemistry

Ларина

2022

Magnetochemistry

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This review summarizes the data on the stereochemical structure of functionalized azoles (pyrazoles, imidazoles, triazoles, thiazoles, and benzazoles) and related compounds obtained by multipulse and multinuclear 1H, 13C, 15N NMR spectroscopy and quantum chemistry. The stereochemistry of functionalized azoles is a challenging topic of theoretical research, as the correct interpretation of their chemical behavior and biological activity depends on understanding the factors that determine the stereochemical features and relative stability of their tautomers. NMR spectroscopy, in combination with quantum chemical calculations, is the most convenient and reliable approach to the evaluation of the stereochemical behavior of, in particular, nitrogen-containing heteroaromatic and heterocyclic compounds. Over the last decade, 15N NMR spectroscopy has become almost an express method for the determination of the structure of nitrogen-containing heterocycles.

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Section: Functional 123-triazole Derivativesmentioning

confidence: 99%

The Structure of Biologically Active Functionalized Azoles: NMR Spectroscopy and Quantum Chemistry

Ларина

2022

Magnetochemistry

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Recent Advances in the Application of Barbituric Acid Derivatives in Multicomponent Reactions

Ziarani

Khademi

Mohajer

et al. 2022

COC

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Barbituric acid is a pyrimidine heterocyclic organic compound, which is pharmacologically active. It is important to build structures containing various medicinal activities. This compound attracts the scientific research community in organic synthesis. It can be used in the synthesis of polyheterocyclic, natural, medicinal compounds, and organic sensors. Herein, the utilization of barbituric or thiobarbituric acid in multicomponent reactions is reported from 2016-2021 in this manuscript.

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Catalyst-free three-component synthesis of hydroxyalkyltriazolylmethylidene barbiturates

Cited by 2 publications

References 52 publications

The Structure of Biologically Active Functionalized Azoles: NMR Spectroscopy and Quantum Chemistry

The Structure of Biologically Active Functionalized Azoles: NMR Spectroscopy and Quantum Chemistry

Recent Advances in the Application of Barbituric Acid Derivatives in Multicomponent Reactions

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