Catalytic transesterification by hybrid silicas containing CnTA+ surfactants

Silva, Laura L.; Zapelini, Iago W.; Cardoso, Dilson

doi:10.1016/j.cattod.2019.07.030

Cited by 5 publications

(2 citation statements)

References 25 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…A series of works focusing on the application of cationic surfactants in drug delivery have been recently reviewed [27], with emphasis given to their use for gene therapy [28,29,30,31], as a template for the synthesis of mesoporous materials [32], and also to their biocidal action against bacteria and fungi [33,34]. In this review, the fundamental approach based on structure-activity correlations between the chemical structure and self-assembly properties of amphiphilic compounds, in combination with their impact on functional activity of supramolecular systems, is taken as a basis for the analysis and recommendations made.…”

Section: Introductionmentioning

confidence: 99%

Cationic Surfactants: Self-Assembly, Structure-Activity Correlation and Their Biological Applications

Zakharova

Pashirova

Doktorovová

et al. 2019

IJMS

115

View full text Add to dashboard Cite

The development of biotechnological protocols based on cationic surfactants is a modern trend focusing on the fabrication of antimicrobial and bioimaging agents, supramolecular catalysts, stabilizers of nanoparticles, and especially drug and gene nanocarriers. The main emphasis given to the design of novel ecologically friendly and biocompatible cationic surfactants makes it possible to avoid the drawbacks of nanoformulations preventing their entry to clinical trials. To solve the problem of toxicity various ways are proposed, including the use of mixed composition with nontoxic nonionic surfactants and/or hydrotropic agents, design of amphiphilic compounds bearing natural or cleavable fragments. Essential advantages of cationic surfactants are the structural diversity of their head groups allowing of chemical modification and introduction of desirable moiety to answer the green chemistry criteria. The latter can be exemplified by the design of novel families of ecological friendly cleavable surfactants, with improved biodegradability, amphiphiles with natural fragments, and geminis with low aggregation threshold. Importantly, the development of amphiphilic nanocarriers for drug delivery allows understanding the correlation between the chemical structure of surfactants, their aggregation behavior, and their functional activity. This review focuses on several aspects related to the synthesis of innovative cationic surfactants and their broad biological applications including antimicrobial activity, solubilization of hydrophobic drugs, complexation with DNA, and catalytic effect toward important biochemical reaction.

show abstract

Section: Introductionmentioning

confidence: 99%

Cationic Surfactants: Self-Assembly, Structure-Activity Correlation and Their Biological Applications

Zakharova

Pashirova

Doktorovová

et al. 2019

IJMS

115

View full text Add to dashboard Cite

show abstract

“…Cationic head groups of surfactants provide their high affnity toward biopolyanions, such as DNA [21,22], cell membranes, and intracellular organelles, such as mitochondrion, thereby initiating the development of a promising area of therapy, the so-called mitochondrion medicine [23,24]. A series of works focusing on the application of CS in drug delivery have been recently reviewed [25,26], with the emphasis given to their use for gene therapy [27,28], as a template for the synthesis of mesoporous materials [29], as well as to their biocidal action against bacteria and fungi [30,31].…”

Section: ■ Introductionmentioning

confidence: 99%

Titrimetric methods for determining cationic surfactants

Blazheyevskіy

Bulska

Tupys

et al. 2022

J. Org. Pharm. Chem.

View full text Add to dashboard Cite

Aim. To generalize and systematize information on titrimetric methods for determining quaternary ammonium compounds (QACs).Results and discussion. The review summarizes and systematizes information on the properties of surfactants, provides their classification, shows the main ways of use in the national economy, and their role in pharmacy and medicine. Currently known titrimetric methods for determining cationic surfactants (СS), in particular quaternary ammonium compounds, which are widely used in medicine and pharmacy, are described and summarized.Conclusions. As a result of the study, the main directions of developing methods for determining QACs by titrimetry methods have been summarized; the disadvantages and advantages of each of the methods described have been shown. In the future, it can be the basis for developing new and more effective methods of analysis.

show abstract