Cataract Forestalling by Antioxidant Activity of Vitamin C; Amelioration of Cataract by Nutritional Intervention

Abbas, Syeda Sarah; Hussain, Saba Javed

doi:10.4172/2167-7689.1000182

Cited by 1 publication

(2 citation statements)

References 10 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Studies have been revealed that antioxidant agents prevent the generation of free radicals that participate in the process of cataract formation (Chang et al, 2013;Abbas and Hussain, 2017). Exposure to environmental stresses (lead to elevated oxidative stress) threatens the eye health (Lu et al, 2019).…”

Section: Discussionmentioning

confidence: 99%

“…Also, higher dietary intake of carotene, vitamins C and E and carbohydrate reduced the risk of cataract, while higher total fat and cholesterol eating increased the risk of cataract. Ascorbic acid could inhibit the proliferation and migration of epithelial cells in the eye lens and reduce the function of Hypoxia-inducible factor 1-alpha (HIF-a) that could be helpful to cataract treatment (Zhao et al, 2015;Abbas and Hussain, 2017).…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

The association between healthy eating index and serum antioxidant indices in patients with different degrees of cataract compared to healthy subjects: a case-control study

Heidari

Jabbari

Babashahi

et al. 2020

NFS

View full text Add to dashboard Cite

Purpose Studies conducted on association between diet and cataract, found conflicting results. This paper aims to investigate the association between healthy eating index (HEI) and serum antioxidant and oxidant indices in patients with different degrees of cataract compared to the healthy subjects. Design/methodology/approach Ninety volunteers (aged > 50 years) were divided into the cataract (n = 45) and healthy control (n = 45) groups in this case-control study. Anthropometric variables, HEI score, serum total oxidant capacity (TOC) and total antioxidant capacity (TAC), blood pressure, physical activity and stress measurements were done for all participants. Findings There was a significant difference in stress level between subgroup of first-degree cataract and healthy controls (16.6 ± 2.3 vs 42.5 ± 29.0, p < 0.001) as well as third-degree cataract (16.6 ± 2.3 vs 75.2 ± 22.6, p < 0.001). Serum TAC was significantly higher in healthy people compared to the first-degree (1.2 ± 0.2 vs 1 ± 0.2, p = 0.002) and third-degree cataract patients (1.2 ± 0.2 vs 1.0 ± 0.2, p = 0.013). Also, serum TOC was significantly lower in healthy controls compared to the first-degree (8.2 ± 1.1 vs 9.2 ± 1.0, p = 0.006) and third-degree cataract patients (8.2 ± 1.1 vs 9.1 ± 1.2, p = 0.015). There was a significant direct correlation between moderation (r = 0.61, p = 0.019) and total score of HEI (r = 0.57, p = 0.031) with serum TAC only in the first-degree cataract patients. Also there was a significant negative correlation between moderation score of HEI with serum TOC in the first-degree cataract patients (r = −0.60, p = 0.025), and there was a significant negative correlation between moderation (r = −0.36, p = 0.017) and total score (r=−0.35, p = 0.021) of HEI and TOC in the total cataract patients. Originality/value To the best of the authors’ knowledge, this is the first study on the assessment of the relationship between components of HEI and serum antioxidant indicators in different types of cataract compared to healthy individuals. It could be a start point for more detailed and large-scaled studies, even intervention studies, in this field.