Catechins and procyanidins in Mediterranean diets

Auger, Cyril; Al-Awwadi, Najim; Bornet, Aurélie; Rouanet, Jean-Max; Gasc, Fabien; Cros, Gérard; Teissèdre, Pierre-Louis

doi:10.1016/j.foodres.2003.11.008

Cited by 106 publications

(72 citation statements)

References 44 publications

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“…Weisser Riesling) had a (+)-catechin content of 79.02 mg/100 g db and 22.67 mg/100 g db respectively, which was lower than our finding. Auger et al (2004) reported that the (+)-catechin in WG from a red grape (Vitis vinifera L.) variety cultivated in the Mediterranean ranged from 9.40 mg/100 g db to 116.50 mg/100 g db, with an average level of 37.70 mg/100 g db, which was lower than our finding (52.30 mg/100 g db). As can be observed, the amounts of (-)-epicatechin present in the GSD (174.10 mg/100 g db) were higher than those in the GSK (51.20 mg/100 g db) and WG (27.92 mg/100 g db).…”

Section: Discussioncontrasting

confidence: 96%

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Study of the Phenolic Composition of Shiraz Red Grape Cultivar (Vitis vinifera L.) Cultivated in North-eastern Thailand and its Antioxidant and Antimicrobial Activity

Butkhup

Chowtivannakul

Gaensakoo

et al. 2016

SAJEV

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The seed, skin and whole grape extract of the red grape cultivar Shiraz, which is widely cultivated in Northeastern Thailand, were investigated. Total phenolic, total flavonoid and total monomeric anthocyanin content ranged from 48.04 to 116.73 g GAE/100g db (dry weight base), 74.82 to 258.69 mg CE/g db, and 5.06 to 55.45 mg/100g db, respectively. Dimeric procyanidin (119.56-484.08 mg/100g db), (+)-catechin (52.30-231.92 mg/100g db), (-)-epicatechin (27.92-174.10 mg/100g db), and gallic acid (4.42-27.80 mg/100g db) were found to be the main flavanols that were present in the seed. Rutin and trans-resveratrol were present in amounts of between 21.13 and 40.05 and 2.85 and 3.60 mg/100g db respectively. All extracts showed remarkable DPPH radical-scavenging activity (EC 50 ), ranging from 0.47 to 2.10 µg/mL. Methanolic extract from the seed and skin were also active against all Gram-positive bacteria, but these exerted less of an inhibiting effect on the growth of the tested Gram-negative bacteria. The activity of the methanolic extract of the seed was effective against B. cereus ATCC 11778, B. subtilis ATCC 6633 and S. faecalis TISTR 459.

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Section: Discussioncontrasting

confidence: 96%

“…These compounds have been proven to be potent antioxidants and to have important biological, pharmacological and medicinal properties (Auger et al, 2004;Kammerer et al, 2004;Maier et al, 2009). Trans-resveratrol was found at low levels in all the samples, with an average of 3.16 mg/100 g db.…”

Section: Discussionmentioning

confidence: 95%

Study of the Phenolic Composition of Shiraz Red Grape Cultivar (Vitis vinifera L.) Cultivated in North-eastern Thailand and its Antioxidant and Antimicrobial Activity

Butkhup

Chowtivannakul

Gaensakoo

et al. 2016

SAJEV

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“…Similarly, the stilbene compounds; trans-resveratrol & trans-piceatannol, which are phytoalexins (Jeandet et al 1991;Hart 1981), could be detected in higher amounts in skin and stem extracts, whereas they could not be detected in seed extracts of both cultivars. The compounds catechin and epicatechin (flavan-3-ols), quercetin and its glycoside rutin (flavonols), and trans-Resveratrol (stilbene) have been proven to be potent antioxidants and to have important biological, pharmacological and medicinal properties (Maier et al 2009;Villano et al 2007;Auger et al 2004;Kammerer et al 2004;Rice-Evans et al 1996).…”

Section: Ndmentioning

confidence: 99%

Phenolic compounds, antioxidant activity and insulinotropic effect of extracts prepared from grape (Vitis vinifera L) byproducts

et al. 2013

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Grape byproducts are a rich source of phenolics having immense medicinal properties, but usually wasted from juice/wine processing industries. The present study investigates the phenolic antioxidants and the insulinotropic effect of extracts prepared from seed, skin and stems of two red wine grape cultivars: Pusa Navarang and Merlot. Pusa Navarang cultivar has shown high amounts of total phenolics (95.8 mg/ml), flavonoids (30.5 mg/ml) and flavan-3-ols (21.8 mg/ml) in seed extract and total anthocyanin (4.9 mg/ml) in its skin extract as compared to Merlot cultivar. As determined using HPLC, higher amounts of catechin hydrate (14909 mg/l) and epicatechin (9299 mg/l) were observed in its seed extract, while quercetin hydrate (5849 mg/l) was abundant in its skin extract. Similarly, ferric reducing antioxidant power (FRAP) and ABTS + . [2,2′-azinobis (3-ethylbenzothiazoline)-6-sulfonic acid] and DPPH. (1,1-diphenyl-2-picrylhy-drazyl) radicals scavenging, were higher in its seed extract, respectively being 134.8 mg/ml of Quercetin equivalent (QE), 18.7 mM of trolox equivalent (TE) and 33.5 mM of TE. Strong correlation was obtained between FRAP and total phenolics, flavonoids and flavan-3-ols contents with correlation coefficients (r 2 ) of 0.915, 0.738 and 0.838 respectively. Interestingly, there was a 2-8 fold increase in insulin secretion by isolated mice pancreatic islets at 5.5 mM and 16.5 mM glucose concentration in presence of various extracts. Overall, the seed, skin and stem byproducts of both cultivars are rich sources of phenolics and antioxidants and represent a source of new insulin secretagogues.

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“…Proanthocyanidins were rarely included in studies before 2004, 62 when a provisional database on the proanthocyanidin content of foods first became available. 58,59,[63][64][65] In these recent studies, the mean total intake of the monomeric flavonoid classes was (Table S1). …”

Section: Flavonoid Intakes In European and Us Cohortsmentioning

confidence: 98%