Catecholamines

Haskins, Steve C.

doi:10.1016/b978-1-4557-0306-7.00157-4

Cited by 5 publications

(2 citation statements)

References 82 publications

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“…Dopamine also stimulates specific dopaminergic receptors (D 1–5 ) that are located in the smooth muscle of renal, coronary, splanchnic, and cerebral vascular beds 34 . Vasopressin is a nonadrenergic vasopressor that binds to specific vasopressin‐1 (V 1 R) receptors present in vascular smooth muscle, which causes vasoconstriction when activated 34,35 …”

Section: Discussionmentioning

confidence: 99%

Use of vasopressors for treatment of vasodilatory hypotension in dogs and cats by Diplomates of the American College of Veterinary Emergency and Critical Care

Murphy

Rishniw²,

Silverstein

2022

J Vet Emergen Crit Care

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Objective: To identify the most common practices of Diplomates of the American College of Veterinary Emergency and Critical Care (DACVECCs) as they relate to the recognition and treatment of hypotension in dogs and cats, particularly concerning the use of vasopressors in vasodilatory shock states. Design: A survey regarding vasopressor use was sent to all active DACVECCs using the Veterinary Information Network. Questions focused on respondent characteristics, method of recognition of hypotension, triggers for initiation of vasopressor therapy, first-and second-line vasopressor choice, and methods of determining response to therapy. Subjects: A total of 734 DACVECCs were invited to participate, and 203 Diplomates (27.7%) completed the survey.Results: For both dogs and cats, the most common first-line vasopressor was norepinephrine (87.9% in dogs and 83.1% in cats). The most common second-choice vasopressor was vasopressin (44.2% in dogs and 39.0% in cats). Cutoff values for initiating vasopressor therapy varied between species and modality used for blood pressure measurement. In general, most DACVECCs chose to initiate vasopressor therapy at a Doppler blood pressure <90 mm Hg or a mean arterial pressure of <60 or <65 mm Hg when using oscillometric or direct arterial blood pressure measurements in dogs and cats.Conclusions: Most DACVECCs adhere to published human guidelines when choosing a first-line vasopressor. However, there is significant variability in blood pressure measurement technique, cutoffs for initiation of vasopressor use, and choice of second-line vasopressors.

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Section: Discussionmentioning

confidence: 99%

Use of vasopressors for treatment of vasodilatory hypotension in dogs and cats by Diplomates of the American College of Veterinary Emergency and Critical Care

Murphy

Rishniw²,

Silverstein

2022

J Vet Emergen Crit Care

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“…The primary catecholamines released by a pheochromocytoma are the alpha‐ and beta‐adrenergic agonists epinephrine, norepinephrine, and dopamine. Epinephrine is a catecholamine with significant effects to increase contractility, heart rate, cardiac output, vasomotor tone, and blood pressure 13 . Specifically, epinephrine's α 1 effects on vascular smooth muscle cause vasoconstriction that increases aortic diastolic pressure, leading to increased coronary perfusion pressure and cerebral perfusion pressure 14 .…”

Section: Discussionmentioning

confidence: 99%

Autoresuscitation and pheochromocytoma multisystem crisis in a dog

Kato

Mallard

2021

J Vet Emergen Crit Care

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Objective: To describe the clinical course of a dog with a pheochromocytoma multisystem crisis that exhibited autoresuscitation after cardiac arrest. Case Summary: An approximately 10-year-old male neutered terrier mix dog presented for collapse. Abdominal imaging was suggestive of a pheochromocytoma, and clinical pathology data and thoracic imaging suggested the presence of a multisystem crisis. The dog developed cardiopulmonary arrest that was followed by autoresuscitation. New or Unique Information Provided:To the authors' knowledge, this is the first report of autoresuscitation in a dog. The phenomenon may have been associated with a pheochromocytoma multisystem crisis. K E Y W O R D Scanine, Lazarus phenomenon, return of spontaneous circulation INTRODUCTIONAutoresuscitation, also known as delayed return of spontaneous circulation (ROSC) or the Lazarus phenomenon, is the unassisted ROSC after cardiac arrest. 1 Autoresuscitation in people was first described in 1982; it is considered to be an exceptionally rare phenomenon, with a reported incidence of 5.95/1,000 in out-of-hospital cardiac arrest. 2The authors of a meta-analysis published in 2015 identified approximately 45 human cases that occurred after futile CPR or after life support was discontinued, and those patients were clinically dead for a range of seconds to 7 minutes before autoresuscitation occurred. Additionally, 3 patients recovered fully with minimal impairments, 1 recovered with severe impairments, and the rest died anywhere from seconds after autoresuscitation to up to 34 days later. 3 The dog in this report had a pheochromocytoma and exhibited features of a metabolic crisis secondary to that tumor. Pheochromocytomas are tumors of neuroectoderm chromaffin cells of the adrenal medulla that secrete catecholamines. Considered uncom-

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Lactic Acidosis in Patients with Solid Cancer

Heneberg

2022

Antioxidants & Redox Signaling

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Catecholamines

Cited by 5 publications

References 82 publications

Use of vasopressors for treatment of vasodilatory hypotension in dogs and cats by Diplomates of the American College of Veterinary Emergency and Critical Care

Use of vasopressors for treatment of vasodilatory hypotension in dogs and cats by Diplomates of the American College of Veterinary Emergency and Critical Care

Autoresuscitation and pheochromocytoma multisystem crisis in a dog

Lactic Acidosis in Patients with Solid Cancer

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