Cathelicidin antimicrobial peptides mediate immune protection of marsupial neonates
Jongbeom Park,
Wenfan Ke,
Aellah Kaage
et al.
Abstract:Marsupial neonates are born with immature immune systems, making them vulnerable to pathogens. While neonates receive maternal protection, they can also independently combat pathogens, though the mechanisms remain unknown. Using the sugar glider (Petaurus breviceps), we investigated marsupial neonatal immune defenses. Cathelicidin antimicrobial peptides are highly expressed in neonates, with their coordinated expression mediated by enhancer sharing within gene clusters and long-range interactions between clust… Show more
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