Catheter Ablation of Paroxysmal Atrial Fibrillation in Patients with Previous Amiodarone‐Induced Hyperthyroidism: A Case–Control Study

Abstract

PV isolation alone has a lower efficacy for preventing recurrence in paroxysmal AF in AIH patients. After repeat ablations, overall freedom from tachyarrhythmias is similar to patients with no history of thyroid dysfunction.

Atrial fibrillation and hyperthyroidism: A literature review

“…After multiple ablations however, the risk of recurrence was noted to be equal in patients with and without AIT. 26 A subsequent study performed by Wang et al studying the safety and efficacy of early radiofrequency catheter ablation in patients with paroxysmal atrial fibrillation complicated with AIT found that pulmonary vein isolation was safe and efficacious with a higher incidence of atrial tachyarrhythmias occurring up to three months post procedure but were not noted 12 months post procedure when matched with controls. 27 In a separate study performed by Machino et al, the efficacy of radiofrequency ablation with pulmonary vein isolation was tested in patients who had a history of hyperthyroidism and were euthyroid for a period of three months and matched with a control group of patients with atrial fibrillation without a history of hyperthyroidism.…”

Biatrial Tachycardia Following Linear Anterior Wall Ablation for the Perimitral Reentry: Incidence and Electrophysiological Evaluations

“…During repeat ablations PV re‐isolation was performed. Pacing maneuvers were used for induction of ATs, as described previously . All stable ATs were targeted for ablation with linear or spot lesions, according to an AT mechanism.…”

History of hyperthyroidism and long-term outcome of catheter ablation of drug-refractory atrial fibrillation

“…11 On the contrary, a case-control study by Milkhaylov and colleagues demonstrated that patients with history of amiodarone-induced hyperthyroidism had higher AF recurrence rate after PVs isolation. 12 Similarly, another study showed that patient with high-normal thyroid function was associated with an increased risk of AF recurrence after catheter ablation. 13 Nevertheless, none of these studies have thoroughly examined the presence of PVs and non-PV ectopic foci in patients with history of hyperthyroidism undergoing AF ablation.…”

“…Previous small studies have reported conflicting results in the outcome of AF ablation in patients with hyperthyroidism. [10][11][12][13] Therefore, we compared the outcome of catheter ablation between euthyroid AF patients with history of hyperthyroidism and normal thyroid AF patients. The electrophysiological characteristics of PVs and atria were compared between the two groups.…”