Catheter Ablation of Ventricular Tachycardias Originating From Right Ventricular Scar in a Patient With Systemic Sclerosis

Costa, Nicholas J.; Lerman, Bruce B.; Cheung, Jim W.

doi:10.1016/s0735-1097(19)33053-0

Cited by 2 publications

(2 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…[ 14 ] Another study reported the efficacy of catheter ablation in a single SSc patient with ventricular tachycardia arising from right ventricular scars, suggesting ablation as a potential therapeutic strategy for treating ventricular arrhythmias in selected severe cases. [ 62 ] These studies, together with others, [ 5 , 63 ] underlie again the prognostic importance of Holter abnormalities (and electrophysiology studies in selected cases) and the clinical significance of primary prevention of SCD in selected SSc populations.…”

Section: Drugs For Cardiac Complications and Cardiologic Therapymentioning

confidence: 93%

Therapeutic strategies for primary heart involvement in systemic sclerosis

Batani,

Dagna,

De Luca

2024

Rheumatology and Immunology Research

View full text Add to dashboard Cite

Primary heart involvement (pHI) is frequent in systemic sclerosis (SSc), even though often underdiagnosed. SSc-pHI has been recently defined as cardiac abnormalities that are predominantly attributable to SSc rather than other causes and/or complications. SSc-pHI represents a major determinant of mortality in SSc, accounting alone for about 12% of disease-related deaths; its early recognition and promptly therapeutic interventions are therefore crucial. Both perfusion defects and myocardial inflammation contribute to the occurrence of myocardial fibrosis that precipitates myocardial remodeling, potentially leading to heart failure and arrhythmic complications. To date, clear evidence and guidelines for effectively managing SSc pHI are not established yet, resulting in a lack of a defined therapeutic algorithm. In this review we summarize the most recent scientific literature on the prevailing therapeutic strategies and interventions to manage SSc-pHI, with particular focus on therapeutic strategies to counteract the 3 major pathogenic events of the disease, i.e. microvascular damage, myocardial inflammation and myocardial fibrosis.

show abstract

Section: Drugs For Cardiac Complications and Cardiologic Therapymentioning

confidence: 93%

Therapeutic strategies for primary heart involvement in systemic sclerosis

Batani,

Dagna,

De Luca

2024

Rheumatology and Immunology Research

View full text Add to dashboard Cite

show abstract

“…83 Another study reported the efficacy of catheter ablation in a SSc patient with VT originating from right ventricular scar, suggesting that ablation could be a potential therapeutic strategy for treating ventricular arrhythmias. 84 These studies, together with others, 8,13 underlie again the prognostic importance of Holter abnormalities (and electrophysiology studies in selected cases) and the clinical significance of primary prevention of sudden death in selected SSc populations.…”

Section: Conventional Cardiologic Therapy and Anti-arrhythmic Drugsmentioning

confidence: 94%

Primary heart involvement in systemic sclerosis, from conventional to innovative targeted therapeutic strategies

Ferlito

Campochiaro

Tomelleri

et al. 2022

Journal of Scleroderma and Related Disorders

View full text Add to dashboard Cite

Primary heart involvement is frequent in systemic sclerosis, even though often sub-clinical, and includes cardiac abnormalities that are predominantly attributable to systemic sclerosis rather than other causes and/or complications. A timely diagnosis is crucial to promptly start the appropriate therapy and to prevent the potential life-threatening early and late complications. There is little evidence on how to best manage systemic sclerosis-primary heart involvement as no specific treatment recommendations for heart disease are available, and a shared treatment approach is still lacking. The objective of this review is to summarize the state of the art of current literature and the overall management strategies and therapeutic approaches for systemic sclerosis-primary heart involvement. Novel insights into pathogenic mechanisms of systemic sclerosis-primary heart involvement are presented to facilitate the comprehension of therapeutic targets and novel treatment strategies.

show abstract

Catheter Ablation of Ventricular Tachycardias Originating From Right Ventricular Scar in a Patient With Systemic Sclerosis

Cited by 2 publications

References 0 publications

Therapeutic strategies for primary heart involvement in systemic sclerosis

Therapeutic strategies for primary heart involvement in systemic sclerosis

Primary heart involvement in systemic sclerosis, from conventional to innovative targeted therapeutic strategies

Contact Info

Product

Resources

About