Catheter-Directed Interventions for Acute Pulmonary Embolism

Liang, Nathan L.; Chaer, Rabih A.; Avgerinos, Efthimios D.

doi:10.1378/chest.15-1011

Cited by 8 publications

(4 citation statements)

References 5 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“… 10 ) The initial results from a prospective multicenter registry evaluating the safety and effectiveness of CDT for acute massive and sub-massive PTE have recently been reported, but no consensus has been reached. 13 , 18 ) Data of treatment outcomes for very severe cases requiring extracorporeal life support treated with catheter-based intervention are limited; we showed that the 30-day mortality rate was 30%. 19 )…”

Section: Resultsmentioning

confidence: 86%

Endovenous Treatment for Acute Massive Pulmonary Thromboembolism

Tajima

Kaneshiro

Takenoshita

et al. 2017

Annals of Vascular Diseases

View full text Add to dashboard Cite

Treatment for venous thromboembolic conditions differs significantly depending on whether the condition is acute or chronic. Endovenous treatment is now available for treating the most severe cases of acute massive pulmonary thromboembolism, and the goal is rapid central clot removal to relieve life-threatening pulmonary circulation. Endovenous catheter interventions include catheter-directed thrombolysis and catheter-assisted thrombus removal. The latter is divided into aspiration thrombectomy, fragmentation, and rheolytic thrombectomy. Data from cohort studies indicate that the clinical outcome and safety after open surgical treatment and endovenous treatment may be comparable. This paper reviews the current approaches to endovenous treatment for acute massive pulmonary thromboembolism, and presents our study of hybrid treatment using a combination of local fibrinolysis, mechanical fragmentation, and clot aspiration.

show abstract

Section: Resultsmentioning

confidence: 86%

Endovenous Treatment for Acute Massive Pulmonary Thromboembolism

Tajima

Kaneshiro

Takenoshita

et al. 2017

Annals of Vascular Diseases

View full text Add to dashboard Cite

show abstract

“…Unclear inclusion criteria, unreported causes of death, and different anticoagulation protocols can be possible explanations for the absence of bleeding events. 23…”

Section: Discussionmentioning

confidence: 99%

Predictors of failure and complications of catheter-directed interventions for pulmonary embolism

Avgerinos

Ali

Liang

et al. 2017

Journal of Vascular Surgery: Venous and Lymphatic Disorders

Self Cite

View full text Add to dashboard Cite

show abstract

“…Unclear inclusion criteria, unreported causes of death, and different anticoagulation protocols can be possible explanations for the absence of bleeding events. 23 In a recent meta-analysis of USAT for acute PE, the major bleeding rate associated with CDI was reported around 0.9%. 24 However, a reanalysis of the same studies using defined homogeneous major bleeding criteria resulted in a major bleeding rate of 3.5%.…”

Section: Discussionmentioning

confidence: 99%

Predictors of Failure and Complications of Catheter-Directed Interventions for Pulmonary Embolism

Avgerinos

Ali

Liang

et al. 2016

Journal of Vascular Surgery: Venous and Lymphatic Disorders

View full text Add to dashboard Cite

Objective: Catheter-directed interventions (CDIs) are increasingly performed for acute pulmonary embolism (PE) as they are presumed to provide similar therapeutic benefits to systemic thrombolysis while decreasing the dose of thrombolytic required and the associated risks. This study aimed to identify factors associated with CDI failure and to describe anticipated complications.Methods: Consecutive patients who underwent CDI for massive or submassive PE between 2009 and 2015 were identified; outcomes and complications were retrospectively collected. CDI clinical failure was defined as major bleeding, perioperative stroke or other major adverse procedurerelated event, decompensation for submassive or persistent shock for massive PE, need for surgical thromboembolectomy, or in-hospital death. Univariate analysis was used to study the factors associated with CDI failure.Results: There were 102 patients who received a CDI during the study period (36 standard catheter thrombolysis, 60 ultrasound assisted, 6 other; age, 59.2 ± 15.9 years; male, 50 [49.0%]; massive PE, 14 [13.7%]). Five patients (4.9%) had a major contraindication and 15 patients (14.7%) had a minor contraindication to systemic thrombolysis. The mean alteplase dose was 28.2 ± 18.8 mg (range, 0-123 mg; three patients had already received systemic lysis). CDI failure occurred in 15 patients (14.7%; 7 in massive PE, 8 in submassive PE). Of these patients, seven had

show abstract

Catheter-Directed Interventions for Acute Pulmonary Embolism

Cited by 8 publications

References 5 publications

Endovenous Treatment for Acute Massive Pulmonary Thromboembolism

Endovenous Treatment for Acute Massive Pulmonary Thromboembolism

Predictors of failure and complications of catheter-directed interventions for pulmonary embolism

Predictors of Failure and Complications of Catheter-Directed Interventions for Pulmonary Embolism

Contact Info

Product

Resources

About