Catheter-Directed Therapy is Safe and Effective for the Management of Acute Inferior Vena Cava Thrombosis

Outcomes of Pharmacomechanical Catheter-directed Thrombolysis for Acute and Subacute Inferior Vena Cava Thrombosis: A Retrospective Evaluation in a Single Institution

“…This variability may be attributed, in part, to the heterogeneous patient population with different involvement of thrombosis. 26 In keeping with the data obtained in the present study, filter-related issues remain one of the most common causes for all IVC thromboses, which compares favorably with the study by Nagarsheth et al 19 In their study, > 80% (n ¼ 21/ 25) patients presenting with acute IVC thrombosis had a previous IVC insertion. However, on multivariate analysis, a previously placed filter was a protective factor for iliocaval patency after endovascular therapy for acute and subacute IVC thrombosis.…”

“…18 Nagarsheth et al studied 25 patients with acute IVC thromboses treated by PCDT. 19 After a median follow-up of 54.3 weeks, all IVCs were patent and only six patients were observed to have chronic DVT within the iliofemoral venous system. Branco et al also reported the application of the Trellis-8 system in treating IVC thrombosis.…”

Venovenous bypass using continuous renal replacement therapy and endovascular inferior vena cava reconstruction to treat bilateral massive iliocaval deep venous thrombosis

“…Historically, treatment of an iliocaval DVT focused on reducing angiospasm, preventing propagation of thrombus, and treating underlying conditions 3 . Open thrombectomy offered the first paradigm shift, and since the 1990s, treatment has focused on resuscitation, anticoagulation, thrombectomy, and thrombolysis 4, 5, 6, 7, 8, 9, 10. Whereas contemporary series of open and endovascular venous treatments have demonstrated similar success when used in combination with iliocaval stenting,9, 10 open thrombectomy is most effective when there is already established outflow through the IVC.…”

Inferior Vena Cava Filter Thrombosis in the Postoperative Neurosurgical Setting: Case Report and Review of the Literature

“…The literature lacks convincing evidence to suggest that of any one of these mechanical interventions is safer or superior to the others. A recent 10-year retrospective review of patients presenting with symptomatic IVC thrombosis concluded that aggressive endovascular treatment of acute IVC thrombosis is safe and effective with an excellent short-term prognosis [ 25 ]. Combined percutaneous mechanical thrombectomy with catheter-directed thrombolysis (CDT) has been shown in several studies to optimize vascular recanalization with minimal thrombolytic dosing [ 12 , 25 - 27 ].…”

“…A recent 10-year retrospective review of patients presenting with symptomatic IVC thrombosis concluded that aggressive endovascular treatment of acute IVC thrombosis is safe and effective with an excellent short-term prognosis [ 25 ]. Combined percutaneous mechanical thrombectomy with catheter-directed thrombolysis (CDT) has been shown in several studies to optimize vascular recanalization with minimal thrombolytic dosing [ 12 , 25 - 27 ]. Although the optimal form of endovascular intervention continues to rest on expert opinion, a mechanical approach is recommended as the first-line intervention in the postoperative setting; the alternative being anticoagulation, which is supported in the literature only for nonsurgical patients [ 28 ].…”