Background: Leuconostoc Mesenteroides are member of the Streptococcae family and currently has been recognized as potential pathogen.this cause describes a nosocomial infection caused by Leuconostoc Mesenteroides in an patient affected by pulmonary Mucoromycosis. Case Report: A 59 year old diabetic and hypertensive male patient was admitted in infectious diseases department with complaint of intermittent cough with hemoptysis,breathlessness since 6 months,then patient was evaluated and found to have pulmonary Mucoromycosis and hence patient was started on antifungal treatment, during the treatment patient started complaining of burning micturition and increased frequency from 3 days, then patient was suspected to have hospital acquired urinary tract infection and investigated accordingly. Urine routine analysis revealed 12-16 pus cells and ultrasound abdomen showed cystitis, hence patient was started on Piperacillin and tazobactam after sending urine for culture. Automated and conventional culture methods showed culture of Leuconostoc Mesenteroides. Conclusion: We concluded that infections caused by Leuconostoc Mesenteroides is serious and should be considered not only in settings of immunocompromised and on prolonged antibiotic use but also in immunocompetent patient.