The current work aims to scrutinize the bioconvection Sutterby nanofluid flow of the Cattaneo-Christov heat and mass flux over a rotating disk. The effects of thermophoresis and Brownian motion receive considerable consideration. The process of analyzing heat and mass transfer phenomena involves taking into account the impacts of thermal radiation and chemical reactions that are susceptible to convective boundary conditions. Firstly, we reduce the PDEs of the physical model to ODEs through alter transformation and then numerically solved the transformed ODEs using Keller Box technique. An analysis of numerical data follows to ascertain the role of numerous flow variables on the flow profiles. Based on the findings, it is evident that an increase in the fluid variable Δ and the porous variable K leads a decrease in the, radial F'(ζ), axial F(ζ) and tangential G(ζ) velocities. Furthermore, we find that the growing values of the thermal radiation Rd variable and the thermal Biot number B_T greatly aid in raising the fluid's temperature. Concentration profile shows decreasing behavior for rising values of Schmidt number Sc but upsurge for solutal Biot number B_C. The microorganism is decayed with greater Lewis number Lb and Peclet number Pe.