2024
DOI: 10.1007/s00432-024-05617-5
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Causal relationship between psychological factors and hepatocellular carcinoma as revealed by Mendelian randomization

Fengming Xu,
Olaf Dirsch,
Uta Dahmen

Abstract: Purpose The impact of psychological factors on the incidence of hepatocellular carcinoma (HCC) in humans remains unclear. Mendelian randomization (MR) study is a novel approach aimed at unbiased detection of causal effects. Therefore, we conducted a two-sample MR to determine if there is a causal relationship between psychological distress (PD), participation in leisure/social activities of religious groups (LARG), and HCC. Methods The genetic summ… Show more

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