2024
DOI: 10.3389/fendo.2024.1348368
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Causal relationships between modifiable risk factors and polycystic ovary syndrome: a comprehensive Mendelian randomization study

Yuheng Zhao,
Jinglin Pang,
Xingyi Fang
et al.

Abstract: BackgroundPolycystic Ovary Syndrome (PCOS) is a heritable condition with an as yet unclear etiology. Various factors, such as genetics, lifestyle, environment, inflammation, insulin resistance, hyperandrogenism, iron metabolism, and gut microbiota, have been proposed as potential contributors to PCOS. Nevertheless, a systematic assessment of modifiable risk factors and their causal effects on PCOS is lacking. This study aims to establish a comprehensive profile of modifiable risk factors for PCOS by utilizing … Show more

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