Causality-Enhanced Multiple Instance Learning With Graph Convolutional Networks for Parkinsonian Freezing-of-Gait Assessment

Guo, Rui; Xie, Zheng; Zhang, Chencheng; Qian, Xiaohua

doi:10.1109/tip.2024.3416052

IEEE Trans. on Image Process.

2024

DOI: 10.1109/tip.2024.3416052

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Causality-Enhanced Multiple Instance Learning With Graph Convolutional Networks for Parkinsonian Freezing-of-Gait Assessment

Rui Guo,

Zheng Xie,

Chencheng Zhang

et al.

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A novel multi-level 3D pose estimation framework for gait detection of Parkinson’s disease using monocular video

He,

You,

Zhou

et al. 2024

Front. Bioeng. Biotechnol.

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IntroductionParkinson's disease (PD) is characterized by muscle stiffness, bradykinesia, and balance disorders, significantly impairing the quality of life for affected patients. While motion pose estimation and gait analysis can aid in early diagnosis and timely intervention, clinical practice currently lacks objective and accurate tools for gait analysis.MethodsThis study proposes a multi-level 3D pose estimation framework for PD patients, integrating monocular video with Transformer and Graph Convolutional Network (GCN) techniques. Gait temporal and spatial parameters were extracted and verified for 59 healthy elderly and PD patients, and an early prediction model for PD patients was established.ResultsThe repeatability of the gait parameters showed strong consistency, with most of the estimated parameters yielding an Intraclass Correlation Coefficient (ICC) greater than 0.70. Furthermore, these parameters exhibited a high correlation with VICON and ATMI results (r > 0.80). The classification model based on the extracted parameter features, using a Random Forest (RF) classifier, achieved an accuracy of 93.3%.ConclusionThe proposed 3D pose estimation method demonstrates high reliability and effectiveness in providing accurate 3D human pose parameters, with strong potential for early prediction of PD.SignificanceThis markerless method offers significant advantages in terms of low cost, portability, and ease of use, positioning it as a promising tool for monitoring and screening PD patients in clinical settings.

show abstract

A novel multi-level 3D pose estimation framework for gait detection of Parkinson’s disease using monocular video

He,

You,

Zhou

et al. 2024

Front. Bioeng. Biotechnol.

View full text Add to dashboard Cite

show abstract

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Causality-Enhanced Multiple Instance Learning With Graph Convolutional Networks for Parkinsonian Freezing-of-Gait Assessment

Cited by 1 publication

References 49 publications

A novel multi-level 3D pose estimation framework for gait detection of Parkinson’s disease using monocular video

A novel multi-level 3D pose estimation framework for gait detection of Parkinson’s disease using monocular video

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