Causas de hospitalización en pacientes con esclerosis múltiple

Maia, Carolina; Costa, Andreia; Abreu, Pedro; Sá, María José

doi:10.33588/rn.6806.2018281

Cited by 8 publications

(9 citation statements)

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“…Los autores partieron de las llamadas "funciones ejecutivas" usando este término, para referirse a un conjunto de capacidades cognitivas y conductuales vagamente relacionadas, estando sin embargo íntimamente ligadas con la región pre-frontal de la corteza cerebral, siendo que todas ellas están bien Tesis Doctoral 102 estructuradas en la jerarquía cognitiva (Maia, 2006;Maia, Perea, Ladera, Silva, Loureiro, Patto et al 2005;Butman t Allegri, 2001).…”

Section: -Procesos Cognitivosunclassified

“…La mayor parte del desempeño del lóbulo frontal, como se plantea anteriormente, está relacionado con las funciones ejecutivas (Maia, 2006;Maia, Perea, Ladera, Silva, Loureiro, Patto et al, 2005). Esta denominación atribuye al lóbulo frontal la ayuda del control de la acción anticipada, de la opción de los objetivos a alcanzar, de planificación, de la selección de la respuesta ajustada más adecuada a las situaciones y de la inhibición de otras; de la atención en el acompañamiento de las acciones en desarrollo y la verificación del resultado de sus acciones/opciones.…”

Section: -Procesos Cognitivosunclassified

“…inhibitorio (Maia, 2006;Maia, Perea, Ladera, Silva, Loureiro Patto et al, 2005; Fuster, 2002 citados en Pino y Werlang, 2001).…”

Section: Tesis Doctoral 103unclassified

“…Generalmente, las alteraciones de cualquier naturaleza en las regiones frontales, interfieren con las funciones ejecutivas y el proceso de tomada de decisiones (Maia, 2006;Maia, Perea, Ladera, Silva, Loureiro, Patto et al 2005 Así, el objetivo general es estudiar y analizar los rendimientos neuropsicológicos de sujetos, del sexo masculino, detenidos, por delitos de abuso sexual, con edades comprendidas entre los 25 y los 51 años.…”

Section: Tesis Doctoral 104unclassified

“…Este test requiere la movilización de un conjunto de capacidades como el lenguaje, la memoria y las funciones ejecutivas. En el lenguaje, la fluidez verbal fonética refleja mejor las capacidades fluidas de los sujetos (Simões, 2003), envolviendo la rapidez de producción lexical y la organización lexical (Baron, 2004), recurriendo, al nivel de iniciativa y de atención, un conjunto de recursos para mantener la producción verbal (Maia, 2006;Maia, Perea-Perea, Ladera, Silva, Loureiro, Patto et al 2005;Simões, 2003).…”

Section: Tesis Doctoral 214unclassified

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Abusadores sexuales: una perspectiva neuropsicológica

Pombo¹,

Pedro²

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Section: -Procesos Cognitivosunclassified

“…inhibitorio (Maia, 2006;Maia, Perea, Ladera, Silva, Loureiro Patto et al, 2005; Fuster, 2002 citados en Pino y Werlang, 2001).…”

Section: Tesis Doctoral 103unclassified

Section: Tesis Doctoral 104unclassified

Section: Tesis Doctoral 214unclassified

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Abusadores sexuales: una perspectiva neuropsicológica

Pombo¹,

Pedro²

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Impact of COVID-19 and system recovery in delivering healthcare to people with multiple sclerosis: a population-based Study

Affinito,

Trama,

Palumbo

et al. 2023

Neurol Sci

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Background COVID-19 pandemic has affected the management of multiple sclerosis (MS). Objective To explore the impact of COVID-19 on healthcare delivery to people with MS and the subsequent recovery of the system. Methods In this population-based study in the Campania Region (Italy), we included people with MS across pre-COVID-19, lockdown, pre-vaccination, and vaccination periods. Differences in continuous outcomes between periods were explored using linear mixed models (annualized hospitalization rate (AHR) and adherence measured as medication possession ratio (MPR)). Differences in disease-modifying treatment (DMT) prescription rates (first DMT prescription, any DMT switch, switch from platform to highly effective DMT, and combination of first DMT prescription and any DMT switch) were assessed using an interrupted time series design. Results Compared with pre-COVID-19, AHR decreased during the lockdown (Coeff = 0.64;95%CI = -0.69, -0.59; p < 0.01), and remained lower during pre-vaccination and vaccination periods. Adherence decreased during pre-vaccination (Coeff = -0.04;95%CI = -0.05, -0.03; p < 0.01) and vaccination periods (Coeff = -0.07;95%CI = -0.08, -0.07; p < 0.01). After the lockdown, there was an increase in any DMT switch (IRR 2.05 95%CI 1.38,3.05; p < 0.01), in switch from platform to highly effective DMTs (IRR 4.45;95%CI 2.48,8.26; p < 0.01) and in first DMT prescriptions (IRR 2.48;95%CI 1.64,3.74; p < 0.01). Conclusions DMT prescriptions quickly returned to pre-pandemic levels, reflecting good health system recovery. However, adherence has remained lower than the past, as from suboptimal care. Assessing long-term COVID-19 impact on MS healthcare is warranted.

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Risk and outcomes of COVID‐19 in patients with multiple sclerosis

Torres

Meca-Lallana

Costa‐Frossard³

et al. 2021

Euro J of Neurology

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Background and purpose Limited information is available on incidence and outcomes of COVID‐19 in patients with multiple sclerosis (MS). This study investigated the risks of SARS‐CoV‐2 infection and COVID‐19‐related outcomes in patients with MS, and compared these with the general population. Methods A regional registry was created to collect data on incidence, hospitalization rates, intensive care unit admission, and death in patients with MS and COVID‐19. National government outcomes and seroprevalence data were used for comparison. The study was conducted at 14 specialist MS treatment centers in Madrid, Spain, between February and May 2020. Results Two‐hundred nineteen patients were included in the registry, 51 of whom were hospitalized with COVID‐19. The mean age ± standard deviation was 45.3 ± 12.4 years, and the mean duration of MS was 11.9 ± 8.9 years. The infection incidence rate was lower in patients with MS than the general population (adjusted incidence rate ratio = 0.78, 95% confidence interval [CI] = 0.70–0.80), but hospitalization rates were higher (relative risk = 5.03, 95% CI = 3.76–6.62). Disease severity was generally low, with only one admission to an intensive care unit and five deaths. Males with MS had higher incidence rates and risk of hospitalization than females. No association was found between the use of any disease‐modifying treatment and hospitalization risk. Conclusions Patients with MS do not appear to have greater risks of SARS‐CoV‐2 infection or severe COVID‐19 outcomes compared with the general population. The decision to start or continue disease‐modifying treatment should be based on a careful risk–benefit assessment.

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Causas de hospitalización en pacientes con esclerosis múltiple

Cited by 8 publications

References 0 publications

Abusadores sexuales: una perspectiva neuropsicológica

Abusadores sexuales: una perspectiva neuropsicológica

Impact of COVID-19 and system recovery in delivering healthcare to people with multiple sclerosis: a population-based Study

Risk and outcomes of COVID‐19 in patients with multiple sclerosis

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