Causes and Risk Factors of Osteoporosis

Oleson, Christina V.; Morina, Amanda B.

doi:10.1007/978-3-319-45084-1_2

Cited by 2 publications

(2 citation statements)

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“…7 The fracture risk depends on bone strength, which is determined by the bone quality and Bone Mineral Density (BMD). 8,9 Moreover, osteoporosis is considered as a metabolic bone disorder accompanied by low mass and weakness of the bones. Plain x-ray images can help the clinicians in the diagnosis of osteoporosis, (Figure 2).…”

Section: Introductionmentioning

confidence: 99%

Association between serum lipid profile, body mass index and osteoporosis in postmenopausal Sudanese women

Alfahal¹,

Ali²,

Modawe³

et al. 2022

Afr H. Sci.

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Background: Epidemiological observations suggest links between osteoporosis and the risk of acute cardiovascular events. Whether the two clinical conditions are linked by common pathogenic factors or atherosclerosis per se remains incompletely understood. The reduction of bone density and osteoporosis in postmenopausal women contributes to elevated lipid parameters and body mass index (BMI). Objective: To investigate the relationship between serum lipid profile, BMI and osteoporosis in postmenopausal women. Materials and Methods: A prospective analytical case control-study conducted in Khartoum north hospital at Khartoum city, capital of the Sudan from April 2017 to March 2018 after ethical approval obtained from the local Research Ethics Committee of Faculty of Medical Laboratories, Alzaeim Alazhary University on the committee meeting number (109) on Wednesday 15th February 2017. A written informed consent was obtained from all participants to participate in the study.Two hundred postmenopausal women were enrolled in the study. The age was studied in one hundred osteoporosis postmenopausal women as a case group and one hundred non-osteoporosis postmenopausal women as control group. The serum lipid profiles were estimated using spectrophotometers (Mandry) and BMI calculated using Quetelet index formula. The data were analysed using SPSS version 16. Results: The BMI, serum total cholesterol, triglyceride, HDL and LDL in case group respectively were (24.846±2.1647, 251.190±27.0135 mg/dl, 168.790 ±45.774 mg/dl, 50.620 ± 7.174 mg/dl, 166.868 ±28.978 mg/dl). While the BMI, serum total cholesterol, triglyceride, HDL and LDL in control group respectively were (25.378 ±3.8115, 187.990 ± 26.611 mg/dl, 139.360±20.290 mg/dl, 49.480 ±4.659 mg/dl, 111.667 ±28.0045 mg/dl). All serum lipid profiles significantly increased (p=0.000) in the case group compared to the controlgroup, except serum HDL was insignificant different between the case and control group and also BMI was insignificant different between the case and control group. There was a positive Pearson’s correlation between BMD and serum total cholesterol (r= 0.832, P<0.01), serum LDL (r = 0.782, P<0.01) and serum triglyceride (r = 0.72, P<0.01). Conclusions: Osteoporotic postmenopausal women had a significant increase in serum lipid profile and BMI. Moreover, we found a positive link between women with cardiovascular diseases and stroke. Keywords: Osteoporosis; Postmenopausal women; Serum lipid profile; Sudan.

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Section: Introductionmentioning

confidence: 99%

Association between serum lipid profile, body mass index and osteoporosis in postmenopausal Sudanese women

Alfahal¹,

Ali²,

Modawe³

et al. 2022

Afr H. Sci.

View full text Add to dashboard Cite

show abstract

“…Brouns and Vermeer [3] verified that a serious number of patients die from complications during the first year of recovery from the fracture; half of those who survive will never have the ability to move around without the assistance of walking aids and wheelchairs. A 10% loss of bone mass in the vertebrae can double the risk of vertebral fractures, and a 10% loss of bone mass in the hip can result in a 2.5 times greater risk of hip fracture [4].…”

Section: Introductionmentioning

confidence: 99%