Causes for diarrhoea and infection with intestinal parasites among HIV positive patients at a referral hospital in Central Ethiopia

Abstract

Background: Intestinal parasitic infections are a major public health challenge in many tropical countries.Opportunistic intestinal coccidia such as Cryptosporidia, Cytoisospora or Cyclospora species are common pathogens which are regularly missed using widely practiced wet mount stool microscopy techniques. Therefore, treatment choices are limited and mostly rely on empirical use of cotrimoxazole.The aim of this study was to determine the prevalence of intestinal parasitosis among HIV-infected individuals with and without diarrhoea at the Asella Teaching and Referral Hospital in Ethiopia. Methods:This institution-based cross sectional study was conducted among 163 ambulatory HIV-infected patients with and without diarrhoea. Stool samples were processed for both wet mount and Kinyoun stain. EDTA blood was collected for analysis of CD4 cell count using BD FACSCount™ Flow Cytometer.

Intestinal parasitic infections and associated factors among people living with HIV/AIDS in Ethiopia: A systematic review and meta-analysis

“…In this study, 22 cross-sectional articles were reported from one city administration and six regions of Ethiopia. Eight studies conducted in Amhara regional state [4,17,18,[30][31][32][33][34], six studies were done in Oromia regional state [28,[35][36][37][38][39], four studies conducted in South Nations, Nationalities and Peoples Regional state (SNNPR) [5,29,40,41], two articles reported from Tigray regional state [16,21], one study reported from Harari regional state [19] and one study was conducted in Oromia region, Afar region and Dire Dawa city administration [42] (Table 1).…”

“…The absence of publication bias was declared using Egger's test statistics with a p-value of 0.31 (Fig 4). The association between CD4+ T-cell counts <200cells/μl and intestinal parasitic infection among HIV/AIDS patients was computed using six studies [5,18,19,37,39,45]. The findings of this meta-analysis showed that HIV/AIDS patients with CD4+ T-cell count <200cells/μl https://doi.org/10.1371/journal.pone.0244887.g004…”