Causes of death among diabetic patients in Denmark

Abstract

Aims/hypothesis To study the distribution of causes of death in the Danish population, and its variation by diabetes status, sex, age and calendar year as well as the years of life lost from the specific causes of death. Methods Persons aged 30-98 years were followed from 1995 to 2008 by linkage of Danish registers. Poisson regression was used to model cause-specific mortality rates by age and calendar time for each specific cause of death, according to sex and diabetes status. The mortality rates were also modelled as a function of age and birth cohort. We computed the distribution of causes of death and years of life lost from specific causes of death due to diabetes. Results During the 14-year study period, patients with diabetes contributed 2.3 million person-years of follow-up and 124,210 deaths, whereas persons without diabetes contributed 45.1 million person-years and 648,020 deaths. The mortality was higher among individuals with diabetes, and the mortality ratio (diabetes vs no diabetes) decreased with age and for all causes and cardiovascular diseases also by calendar time. The effect of sex on the association between diabetes and mortality varied with age and cause of death. About 9 years of life were lost to diabetes at age 30 years, and 3 years at age 70 years. Conclusions/interpretation Age-specific mortality is higher among people with diabetes, and rate ratios vary with age, sex, calendar period and cause of death. The distribution of causes of death was similar for persons with and without diabetes.

Work, Diabetes and Obesity: A Seven Year Follow-Up Study among Danish Health Care Workers

“…It is estimated that types 1 and 2 diabetes collectively cause the loss of an average of 9 years of life at age 30 years and 3 years at age 70: the relative risk for cardiovascular disease among those with diabetes, compared to those without it, is 3.5 at age 50 [15]. We are unable to distinguish between type 1 and type 2 diabetes in terms of these effects.…”

“…However, the register does not distinguish between type 1 and type 2 diabetes. DNDR has been validated and found to be reliable as a source for linkable information on diabetes at a national level [15], [30].…”

Preventable Major Cardiovascular Events Associated With Uncontrolled Glucose, Blood Pressure, and Lipids and Active Smoking in Adults With Diabetes With and Without Cardiovascular Disease: A Contemporary Analysis

“…Coronary heart disease and stroke are the leading causes of excess morbidity, mortality, and cost in adults with diabetes (4). Advances in medical care and improvements in cardiovascular (CV) risk factor control have resulted in the reduction of CV events and deaths among adults with diabetes (2,3).…”

Association of impaired fasting glucose, diabetes and dietary patterns with mortality: a 10-year follow-up cohort in Eastern China

“…It is well known that people with diabetes have a lower life expectancy. In Western countries, numerous data show that diabetes increases the risk of mortality, especially from cardiovascular disease (CVD) [4][5][6][7][8]. However, studies in Asia in this area are limited [9].…”