Causes of death in infants admitted to <scp>A</scp>ustralian neonatal intensive care units between 1995 and 2006

Feng, Yvonne; Abdellatif, Mohamed; Bajuk, Barbara; Lui, Kei; Oei, Ju Lee

doi:10.1111/apa.12039

Cited by 14 publications

(21 citation statements)

References 27 publications

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“…In contrast, the proportions of deaths due to congenital anomalies (n=4, 4.1%) included tracheal stenosis, multiple dysmorphic feathures without definite diagnosis and cyanotic heart anomalies were relatively lower than those reported in other studies 6,25,31) , likely because infants who required cardiac or abdominal surgery were transferred to other hospitals due to a lack of professional manpower in our unit. There were 99 cases who were transferred to other hospitals over the 13-year period studied, mainly because of abdominal operations for congenital gastrointestinal obstruction or NEC (n=43), and cardiac manage ment for suspected congenital heart defects (n=24).…”

Section: Discussioncontrasting

confidence: 74%

Deaths in the Neonatal Intensive Care Unit between 2002 and 2014

Park

Kim

2016

Neonatal Med

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Purpose: To report the causes and patterns of death among infants admitted to our neonatal intensive care unit (NICU) over a 13-year period. In addition, we analyzed trends regarding the type of end-of-life care provided. Results: Of the 5,223 admissions to our NICU, 97 neonates died. The overall mortality rate was 1.9%. The most common cause of death was sepsis (15%). At a lower gestational age, infants died of extreme prematurity and complications of prematurity. Among term infants, the principal cause of death shifted to hypoxic ischemic encephalopathy and asphyxia. A total of 63 infants (64.9%) received maximal inten sive care, and 34 infants (35%) had redirection of intensive care. During this period, the proportion of death after redirection of care increased from 30.6% to 39.6%. Infants decided to forgo life-sustaining care before death had significantly lower gestational ages and lower birth weights (30.5 vs. 27.1 weeks, P=0.005; 1,528 vs. 1,063 g, P=0.025). Conclusion: Infection remained an important cause of death for neonate, particularly for preterm infants. The proportion of infants who had redirectoin of care before death was increased, suggesting that quality-of-life should be considered an important factor in the decision-making process for the infant, parents, and medical staff.

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Section: Discussioncontrasting

confidence: 74%

Deaths in the Neonatal Intensive Care Unit between 2002 and 2014

Park

Kim

2016

Neonatal Med

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“…Some of the reasons for exclusion were the absence of numerical mortality rates, lack/absence of relevant information regarding NICU mortality, and repeat data. Of the 20 remaining articles ( 20 – 39 ), eight reported on any infants admitted to NICUs ( 20 , 22 , 25 , 33 – 37 ), three reported on the outcomes of extremely low birth weight infants (≤500 g, 401–1,000 g) ( 21 , 26 , 38 ), three others reported on the outcomes of very low birth weight infants (≤1,500 g) ( 30 , 32 , 39 ), two discussed all in-hospital deaths ( 23 , 28 ), two focused on the outcomes of very preterm infants [<32 weeks gestational age (GA)] ( 24 , 29 ), one involved the outcomes of preterm infants [<37 weeks GA] ( 31 ) and one reported on the outcomes of preterm infants with a birth weight of ≤1,500 g ( 27 ) (Table 1 ).…”

Section: Resultsmentioning

confidence: 99%

A Selected Review of the Mortality Rates of Neonatal Intensive Care Units

Chow

Popovic

et al. 2015

Front. Public Health

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IntroductionNewborn babies in need of critical medical attention are normally admitted to the neonatal intensive care unit (NICU). These infants tend to be preterm, have low birth weight, and/or have serious medical conditions. Neonatal survival varies, but progress in perinatal and neonatal care has notably diminished mortality rates. In this selected review, we examine and compare the NICU mortality rates and etiologies of death in different countries.MethodsA literature search was conducted in Ovid MEDLINE, OLDMEDLINE, EMBASE Classic, and EMBASE. The primary endpoint was the mortality rates in NICUs. Secondary endpoints included the reasons for death and the correlation between infant age and mortality outcome. For the main analysis, we examined all infants admitted to NICUs. Subgroup analyses included extremely low birth weight infants (based on the authors’ own definition), very low birth weight infants, very preterm infants, preterm infants, preterm infants with a birth weight of ≤1,500 g, and by developed and developing countries.ResultsThe literature search yielded 1,865 articles, of which 20 were included. The total mortality rates greatly varied among countries. Infants in developed and developing countries had similar ages at death, ranging from 4 to 20 days and 1 to 28.9 days, respectively. The mortality rates ranged from 4 to 46% in developed countries and 0.2 to 64.4% in developing countries.ConclusionThe mortality rates of NICUs vary between nations but remain high in both developing and developed countries.

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“…Until the 1970s, early death, mostly from respiratory complications, was a common consequence of preterm birth. Over the last few decades, innovative strategies such as the development of appropriately sized infant ventilators, exogenous surfactant and antenatal steroids have decreased both the gestational limits of viability as well as the mortality rates for preterm infants . Preterm babies are now surviving in greater numbers and for longer.…”

Section: Introductionmentioning

confidence: 99%