Causes of endogenous uveitis in cats presented to referral clinics in North Carolina

Jinks, Maggie R.; English, Robert V.; Gilger, Brian C.

doi:10.1111/vop.12324

Cited by 29 publications

(49 citation statements)

References 48 publications

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“…In cats without FIP that do not present with effusion, uveitis is common and ocular signs (with or without involvement of the central nervous system) can be noticed in 60% of the affected cats [12,131]. Secondary to the inflammation of ocular structures and breakdown of the blood-ocular barrier, FCoV-bearing macrophages are present in the eye and FCoV antigen can be detected immunocytochemically within macrophages in the aqueous humor [47,132].…”

Section: Detection Of Fcov Antigen In Macrophages By Immunostainingmentioning

confidence: 99%

“…To date, there have been very few studies that evaluated this sample material for analysis by RT-PCR in a small number of cats with FIP (Table 13). Additionally, a case report demonstrated positive RT-PCR in the aqueous humor of 3/10 cats with uveitis; however, there were no clear-defined FIP and control groups [131].…”

Section: Detection Of Fcov Rna By Reverse Transcriptase Polymerasementioning

confidence: 99%

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Diagnosis of Feline Infectious Peritonitis: A Review of the Current Literature

Felten

Hartmann

2019

Viruses

124

164

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Feline infectious peritonitis (FIP) is a fatal disease that poses several challenges for veterinarians: clinical signs and laboratory changes are non-specific, and there are two pathotypes of the etiologic agent feline coronavirus (FCoV), sometimes referred to as feline enteric coronavirus (FECV) and feline infectious peritonitis virus (FIPV) that vary fundamentally in their virulence, but are indistinguishable by a number of diagnostic methods. This review focuses on all important steps every veterinary practitioner has to deal with and new diagnostic tests that can be considered when encountering a cat with suspected FIP with the aim to establish a definitive diagnosis. It gives an overview on all available direct and indirect diagnostic tests and their sensitivity and specificity reported in the literature in different sample material. By providing summarized data for sensitivity and specificity of each diagnostic test and each sample material, which can easily be accessed in tables, this review can help to facilitate the interpretation of different diagnostic tests and raise awareness of their advantages and limitations. Additionally, diagnostic trees depict recommended diagnostic steps that should be performed in cats suspected of having FIP based on their clinical signs or clinicopathologic abnormalities. These steps can easily be followed in clinical practice.

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Section: Detection Of Fcov Antigen In Macrophages By Immunostainingmentioning

confidence: 99%

Section: Detection Of Fcov Rna By Reverse Transcriptase Polymerasementioning

confidence: 99%

Diagnosis of Feline Infectious Peritonitis: A Review of the Current Literature

Felten

Hartmann

2019

Viruses

124

164

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“…Treatment of FIP until recently has focused on maintenance therapy and stimulation of cellmediated immunity with interferon or feline recombinant interferon [61].…”

Section: Treatment and Prevention Of Fipmentioning

confidence: 99%

Feline coronavirus infection

et al. 2021

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The main feature of feline coronavirus infection is its manifestation in the form of peritonitis. Feline infectious peritonitis is a highly lethal disease that lacks primary prevention and therapy. Therefore, feline infectious peritonitis is an epizootic problem in the near future. In our review, we demonstrate the current clinical, diagnostic, and therapeutic interventions for feline infectious peritonitis, as well as hypotheses of origin.

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“…Yaş formda kedilerde pleuritis ve peritonitis ile birlikte göğüs veya karın boşluğunda proteinden zengin altın sarısı renginde sıvı birikimlerine neden olmaktadır. Kuru formda ise çeşitli organlarda yaygın granulamatöz veya pyogranulamatöz lezyonlar gelişmektedir (1,12,13,(16)(17)(18)(19). Kedilerde FİP infeksiyonları çoğu zaman subklinik seyretmekte ve hasta kediler yaşadıkları sürece virüsü taşır ve etrafa yayarlar.…”

Section: Introductionunclassified

Feline infeksiyöz peritonitisli kedilerde bazı hematolojik ve biyokimyasal Parametrelerin Araştırılması

Gokce

Cengiz

2019

Veterinary Journal of Mehmet Akif Ersoy University

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ÖZ Araştırmanın amacı felin infeksiyöz peritonitisli (FİP) kedilerde bazı biyokimyasal ve hematolojik parametrelerin araştırılmasıdır. Ayrıca kuru form ve yaş from FİP'li kediler arasında analiz edilen bu parameterlerde farlılıkların belirlenmesi de hedeflenmiştir. Çalışmada klinik belirtiler gösteren, sadece Feline Coronavirus (FCoV) Ag veya FCoV Ab pozitif olan 20 adet (çalışma grubu) ve klinik olarak sağlıklı tüm testlerden negatif olan 10 adet (kontrol grubu) kedi kullanıldı. Ayrıca, klinik ve nekropsi bulguları ışığında 20 FİP'li kedi eşit olarak kuru ve yaş from FİP'li olarak iki gruba ayrıldı. Bu hayvanların klinik muayeneleri, hematolojik ve biyokimyasal analizleri yapılarak elde edilen değerler kayıt altına alındı. Çalışmada, yapılan klinik muayenede FİP'li kedilerin sadece solunum sayılarının kontrol grubuna göre daha yüksek olduğu (p<0.01), kalp frekansı ve rektal derecelerinde ise önemli farklılıkların olmadığı belirlenmiştir. Yapılan hematolojik analizler sonucunda FİP'li kedilerin total lökosit (WBC) (p<0.01), granulosit (p<0.01) ve monosit (p<0.01) sayılarında kontrol grubuna göre önemli düzeyde artışların olduğu buna karşın total eritrosit (p<0.01) ve lenfosit sayıları (p<0.05) ile hemoglobin (HGB) konsantasyonlarının (p<0.05) ise kontrol grubuna göre anlamlı düzeyde düşük olduğu saptanmıştır. Biyokimyasal analizler sonucunda FİP'li kedilerin alanin aminotransferaz (ALT) (p<0.01), laktat dehidrojenaz (LDH) (p<0.05), alkalen fosfotaz (ALP) (p<0.05), total bilirubin (TB) (p<0.01), total protein (TP) (p<0.05) ve globülin (G) (p<0.001) değerlerinin kontrol grubuna göre istatistiksel olarak anlamlı düzeyde yüksek, albumin (A) (p<0.05) ve A/G (p<0.001) oranının ise daha düşük olduğu saptandı. Kuru formda bulunan kedilerin BUN, TP, A, G değerlerinin yaş formda bulunan kedilerin değerlerine göre daha yüksek, A/G oranının ise daha düşük olduğu belirlendi. Sonuç olarak, bu çalışmada elde edilen bulgular FİP'li kedilerin hematopoetik sistemi yanında karaciğer ve böbrek fonksiyonlarınında bu infeksiyondan negatif yönde etkilendiğini ortaya koymaktadır. Investigation of some hematologic and biochemical parameters in cats with infectious peritonitis ABSTRACT The aim of the present study was to investigate some hematologic and biochemical parameters in cats with feline infectious peritonitis (FIP). In addition to these, the differences in these parameters between dry and wet form of FIP was also evaluated. In the study, 20 cats, showing clinical symtoms of FIP and positive to only either FCoV Ag or FCoV Ab were used. Ten healthy cats negative to FCoV Ag and FCoV Ab tests were aslso used as Control goup. According to the clinica and necropsy findings, 20 cats with FIP were divided into two groups equally as dry and wet from FIP. The cats were clinically examined, hematologic and biochemical parameters were analysed and all the obtained parameters were recorded. In cats with FIP, only respiratory rates were found to high compared to that of the control group (p<0.01), whilst there were no statistically significant...

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Causes of endogenous uveitis in cats presented to referral clinics in North Carolina

Cited by 29 publications

References 48 publications

Diagnosis of Feline Infectious Peritonitis: A Review of the Current Literature

Diagnosis of Feline Infectious Peritonitis: A Review of the Current Literature

Feline coronavirus infection

Feline infeksiyöz peritonitisli kedilerde bazı hematolojik ve biyokimyasal Parametrelerin Araştırılması

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