Causes of sudden natural death in Jamaica: a medicolegal (coroner’s) autopsy study from the University Hospital of the West Indies

Escoffery, Carlos; Shirley, Suzanne E

doi:10.1016/s0379-0738(02)00268-2

Cited by 45 publications

(37 citation statements)

References 8 publications

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“…The previous studies have also shown the similar findings. 13 Approximately 3.5% of cases were due to other respiratory diseases such as aspiration, chronic obstructive embolism and lung cancer.…”

Section: Discussionmentioning

confidence: 99%

A study of sudden natural deaths in medico legal autopsies in University Malaya Medical Centre (UMMC), Kuala Lumpur

Kumar

San

Idwan

et al. 2007

Journal of Forensic and Legal Medicine

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Section: Discussionmentioning

confidence: 99%

A study of sudden natural deaths in medico legal autopsies in University Malaya Medical Centre (UMMC), Kuala Lumpur

Kumar

San

Idwan

et al. 2007

Journal of Forensic and Legal Medicine

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“…The incidence of sudden unexpected natural deaths is known to vary in different parts of the world and may reflect the respective levels of development of the individual country's death registration and medico-legal autopsy systems [3,[5][6][7][8][9][10].…”

Section: Introductionmentioning

confidence: 99%

An autopsy review of sudden unexpected natural deaths in a suburban Nigerian population

Pelemo

Sabageh

Komolafe

et al. 2014

Popul Health Metrics

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Background: The pattern of diseases causing sudden unexpected natural deaths is a function of the prevalent disease pattern in the general population. This pattern appears to be changing in Nigeria in response to changing demographics and lifestyle. Methods: This was a descriptive retrospective autopsy-based review of cases of sudden unexpected natural deaths seen at the Obafemi Awolowo University Teaching Hospitals Complex in Ile-Ife, Nigeria (OAUTHC) over a 10-year period. Analysis was done for differences in proportion using Chi square (p is significant at <0.05) by SPSS version 15. Results: Sudden unexpected natural deaths accounted for 13.4% of all medico-legal autopsies. The male to female ratio was 2.1:1, and the mean age was 43.1 years ± 19.5 SD. Cardiovascular (28.3%), respiratory (18.2%), and central nervous system (12.6%) disorders were the major groups of causes. About 64.4% of cardiovascular deaths were due to hypertensive heart disease. Bacterial pneumonia, intracerebral haemorrhage, and breast carcinoma accounted for 34.4%, 60.0%, and 52.6% of respiratory, central nervous system, and cancer-related deaths respectively. Infectious causes predominated in all age groups below 40 years and above 70 years while hypertensive disorders predominated between 40 and 70 years. Only 16.9% of cases occurred while the patient was admitted to the hospital.

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“…In one series of 306 autopsies of patients with SCD, death was noted to be sudden and unexpected in 40.8%(24). And while the most common causes of death in adult patients with SCD have been reported to be ACS, infection, stroke, pHTN, and sickle cell-related lung injury(9, 11, 13–15, 23–29), the cause of death is commonly unknown(24, 27, 28, 30). …”

Section: Introductionmentioning

confidence: 99%

Cardiopulmonary complications leading to premature deaths in adult patients with sickle cell disease

et al. 2009

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Sickle cell disease (SCD) is associated with early mortality. We sought to determine the incidence, cause, and risk factors for death in an adult population of patients with SCD. All patients aged ≥18 years seen at the Adult Sickle Cell Center at Duke University Medical Center between January 2000 and April 2005 were enrolled. Forty-three patients (21 males and 22 females) died during the study period. Median age of survival was 39 years for females (95% CI 34–56), 40 years for males (95% CI 34–48), and 40 years overall (95% CI 35–48). Cardiac causes of death accounted for 25.6% (11/43 patients); pulmonary, 14.0% (6 patients); other SCD related, 32.6% (14 patients); unknown, 14.0% (6 patients); and others, 14.0% (6 patients). Pulseless electrical activity arrest, pulmonary emboli, multi-organ failure, and stroke were the most frequent causes of death. Among the deceased patients, the most common pre-morbid conditions were cardiopulmonary: ACS/pneumonia (58.1%), pHTN (41.9%), systemic hypertension (HTN) (25.6%), congestive heart failure (CHF) (25.6%), myocardial infarction (20.9%), and arrhythmias (14.0%). Tricuspid regurgitant jet velocity (TRv) was significantly higher (3.1 m/s vs. 2.6 m/s, p<0.001) and hemoglobin significantly lower (8.3 g/dL vs. 9.2 g/dL, p<0.05) in deceased patients as compared to patients who lived, respectively. With improved preventive and therapeutic advances, including hydroxyurea therapy, acute complications such as infection are no longer the leading cause of death; instead causes of death and pre-morbid conditions are shifting to chronic cardiopulmonary complications. Further, arrhythmia leading to premature death is under-recognized in SCD and warrants further investigation.

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Causes of sudden natural death in Jamaica: a medicolegal (coroner’s) autopsy study from the University Hospital of the West Indies

Cited by 45 publications

References 8 publications

A study of sudden natural deaths in medico legal autopsies in University Malaya Medical Centre (UMMC), Kuala Lumpur

A study of sudden natural deaths in medico legal autopsies in University Malaya Medical Centre (UMMC), Kuala Lumpur

An autopsy review of sudden unexpected natural deaths in a suburban Nigerian population

Cardiopulmonary complications leading to premature deaths in adult patients with sickle cell disease

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