Causes of Superinfections: Deadly Bacteria of Tuberculosis

Abstract

The aim: To improve early diagnosis of drug-resistant superbacteria and interrupt the ways of its formation through molecular technological and surgical methods. Materials and methods: The operated patients were divided into two groups: group 1 – 351 (51.25 %) patients, who were operated with the use of minimally invasive technologies, and this was the main group; group 2 – 334 (48.75 %) patients who were operated on open wide thoracotomy, which was the comparison group. Among 351 patients in the main group, in 301 – acute pleural tuberculous empyema was detected, and in 50 – chronic one. Among patients in the comparison group, acute pleural empyema was observed in 284 patients and chronic in 50 patients. Results: According to our data, video thoracoscopy is a highly informative method of diagnosis of pleural effusions, detection of pleural tuberculous empyema in the first, second and third stages of its development. Conclusions: The introduction of modern molecular-geneticand surgical technologies will allow to accurately establish the etiology process, to conduct the identification of pathogen microorganisms and to determine the phenotymetric and genotytypical sensitivity of bacteria to Antimycobacterial drugs. Such diagnostics will promote effective treatment of patients who are already infected with persistent strains of bacteria and viruses.

Comparison of clinical effects between regional arterial embolization combined with surgery and simple surgery in the treatment of tuberculosis-destroyed lung—a retrospective comparative cohort study

“…Tuberculosis-destroyed lung refers to irreversible destructive and extensive changes in lung tissue caused by repeated infection of mycobacterium tuberculosis. It can manifest as single or multiple caseous cavities or tuberculous fibrous cavities, localized bronchiectasis, mediastinal displacement, thickening of pleural adhesions, and loss of pulmonary function (1)(2)(3). Conservative treatment with drugs is not effective (4).…”

Analysis of prevalence of adverse events connected with anti-tuberculosis drugs during pregnancy: A meta-analysis

“…Tuberculosis is primarily transmitted through the inhalation of airborne droplets containing Mycobacterium tuberculosis [ 5 ]. The risk factors for TB transmission and infection include close contact with individuals who have active TB, compromised immune systems, and conditions such as malnutrition and HIV/AIDS [ 6 ].…”