Cauterization of the germinal nail matrix using phenol applications of differing durations: A histologic study

Becerro-de-Bengoa-Vallejo, Ricardo; Iglesias, Marta Elena Losa; Tirado, Fermín Viejo; Pardo, Rosario Serrano

doi:10.1016/j.jaad.2012.05.002

Cited by 24 publications

(14 citation statements)

References 43 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…There are numerous surgical procedures and modifications described in the surgery of ingrown nail [1][2][3][4][5], its causes, and contributing risk factors [6]. There exist various non-incisional surgical options, such as the gold standard procedure, chemical matricectomy with 88% phenol solution, and its modifications [7][8][9], such as the modification which eliminates cauterized tissue via thorough curettage [1], or different duration for the application time of phenol [10].…”

Section: Introductionmentioning

confidence: 99%

“…This option shows beneficial effects, such as strong antiseptic properties, production of necrosis during protein coagulation, and reduction of pain due to nerve fiber demyelination in the nail unit [11,12]. Nevertheless, chemical matricectomy with 88% phenol solution may produce a delay in the healing time (between 21 and 42 days) related to tissue destruction, excessive drainage, and an adverse reaction to the phenol solution [10,[13][14][15]. On the other hand, incisional surgical options are indicated for advanced stages with hypertrophy of the nail folds.…”

Section: Introductionmentioning

confidence: 99%

“…First, a wedge resection of soft tissue is carried out, eliminating the germinal cells of the matrix and of the nail bed, and later a curettage is done of the surgical zone. The chemical matricectomy with phenol has the highest effectiveness rate [16], but it has a long healing time [7][8][9][10][11][12][13][14][15]. Aesthetic reconstruction has as advantages, a shorter healing time with respect to chemical matricectomy with phenol with a similar effectiveness [1].…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

The Treatment of Ingrown Nail: Chemical Matricectomy With Phenol Versus Aesthetic Reconstruction. A Single Blinded Randomized Clinical Trial

Muriel-Sánchez

Becerro-de-Bengoa-Vallejo

Montaño‐Jiménez

et al. 2020

JCM

View full text Add to dashboard Cite

Background: In onychocryptosis surgery, incisional and non-incisional matricectomy is indicated according to the stage. The chemical matricectomy with 88% phenol solution is the gold standard and a wedge resection is indicated for more advanced stages. The aesthetic reconstruction has the advantages of the incisional procedure without eponychium incisions and an effectiveness similar to the chemical matricectomy with phenol. Objective: To compare the recurrence and the healing time between the chemical matricectomy with phenol and the aesthetic reconstruction. Methods: A comparative, prospective, parallel, randomized, and one-blinded clinical trial was registered with the European Clinical Trials Database (EudraCT) with identification number 2019-001294-80. Thrity-four patients (56 feet) with 112 onychocryptosis were randomized in two groups. Thirty-six were treated with chemical matricectomy with phenol and 76 with aesthetic reconstruction. Each patient was blind to the surgical procedure assigned by the investigator. The primary outcome measurements were healing time and recurrence. The secondary outcome measurements were post-surgical bleeding, pain, inflammation, and infection rate. Results: The aesthetic reconstruction procedure presents a shorter healing time (8.2 ± 1.4 days vs. 21.3 ± 3.1 days; p < 0.001) with a similar recurrence rate (p = 0.98). Post-operatory bleeding, pain, inflammation, and the infection rate did not show significant differences (p > 0.05). Conclusions: The aesthetic reconstruction presents a shorter healing time, favoring the patients’ recuperation, with a recurrence similar to the chemical matricectomy with 88% phenol solution.

show abstract

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

The Treatment of Ingrown Nail: Chemical Matricectomy With Phenol Versus Aesthetic Reconstruction. A Single Blinded Randomized Clinical Trial

Muriel-Sánchez

Becerro-de-Bengoa-Vallejo

Montaño‐Jiménez

et al. 2020

JCM

View full text Add to dashboard Cite

show abstract

“…In a study carried out in 2012 using cadaveric fresh specimens, Becerro de Bengoa Vallejo et al [7] assessed the phenol application time required for complete denaturation of the nail matrix, arguing that identifying the optimal time required to destroy the matrix without causing further damage should reduce the complications. It was found that after a 1-min application of 88% phenol solution, only superficial damage to the nail bed epithelium was noted, with the basal layer primarily intact.…”

Section: Introductionmentioning

confidence: 99%

“…After a 3-min application, full-thickness necrosis of the nail bed epithelium was noted in 6 of the 10 specimens. After 4-, 5-, and 6-min applications, full-thickness necrosis of the nail bed epithelium was noted, and the basal layer was completely destroyed in all 30 specimens [7]. Therefore, 4 min seems to be the ideal timing.…”

Section: Introductionmentioning

confidence: 99%

The Recurrence of Onychocryptosis when Treated with Phenolization: Does Phenol Application Time Play a Role? A Follow-Up Study on 622 Procedures

Montesi

Lazzarino²,

Galeone

et al. 2019

Dermatology

View full text Add to dashboard Cite

Introduction: Chemical matricectomy using phenol (CMP) is a recognized treatment option for onychocryptosis. However, the appropriate phenol application time to achieve nail matrix destruction is still unknown. Optimal ablation leads to low recurrence rates. The aim of this research was to assess the recurrence rate of onychocryptosis in a cohort of 622 consecutive patients treated with a 4-min CMP. Methods: We recruited all patients undergoing a 4-min CMP for onychocryptosis at the Istituto Podologico Italiano, Rome, Italy, in 2008–2017. Postoperative follow-up visits were set at 24 h, 7, 14, 21, and 28 days, 6 months, and 1 year after surgery. We used adjusted logistic regression to evaluate the potential risk factors for the disease recurrence including age, gender, toe shape, comorbidities, and disease localization. Results: The risk of recurrence in all patients treated with a 4-min CMP was 1.1% (n = 622, 95% CI = 0.5%–2.3%). In the subgroup of patients with cardiovascular disease (n = 39) the recurrence risk was 5.1% (95% CI = 0.61–7.3). Young age was also associated with increased odds of recurrence (p = 0.036). Conclusion: In this observational study, 4 min with no interruptions seems to be the appropriate application time of phenol when using CMP for the treatment of onychocryptosis. A randomized controlled trial should be carried out to confirm our results.

show abstract

Acquired Disorders of the Nails and Nail Unit

Berker

Richert

Baran

2016

Rook's Textbook of Dermatology, Ninth Edition

View full text Add to dashboard Cite

This chapter deals with all aspects of the nails in health and disease apart from hereditary nail disorders and fungal infections of the nails which are addressed in Chapters 69 and 32, respectively. Nail biology and growth establishes the basis for an understanding of how the nail may be affected by disease processes and their treatment. The significance of nail signs, which may be an important indicator of systemic diseases, is fully discussed before individual disorders of the nail and perionychium are described. The section on dermatoses affecting the nails includes the main categories of inflammatory and neoplastic diseases seen at other sites in the skin, but as expressed in the nail unit. The diagnostic imaging of the nail and nail surgery sections highlight special considerations required in managing disorders of the nail. Finally, the reader is introduced to cosmetic procedures used on nails and problems which may arise from them.

show abstract

Cauterization of the germinal nail matrix using phenol applications of differing durations: A histologic study

Cited by 24 publications

References 43 publications

The Treatment of Ingrown Nail: Chemical Matricectomy With Phenol Versus Aesthetic Reconstruction. A Single Blinded Randomized Clinical Trial

The Treatment of Ingrown Nail: Chemical Matricectomy With Phenol Versus Aesthetic Reconstruction. A Single Blinded Randomized Clinical Trial

The Recurrence of Onychocryptosis when Treated with Phenolization: Does Phenol Application Time Play a Role? A Follow-Up Study on 622 Procedures

Acquired Disorders of the Nails and Nail Unit

Contact Info

Product

Resources

About