Caution in the Use of Lidocaine Infusion in the Surgical Patient

Drage, Mike

doi:10.1213/00000539-199811000-00051

Cited by 3 publications

(4 citation statements)

References 5 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…56 Another RCT on the same topic failed to evaluate the pain-control efficacy because of the increased number of wound infections. 58…”

Section: Discussionmentioning

confidence: 99%

“…56 Another RCT on the same topic failed to evaluate the pain-control efficacy because of the increased number of wound infections. 58 It is worth noting that there are some local anaesthesiaassociated adverse effects on wound healing that should be kept in mind. 59,60 While Barr et al 30 declared the safety of a single local injection, we may speculate that the placement of a catheter can affect incision healing and prolong the ICU stay.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Evaluation of Different Pain-Control Procedures for Post-cardiac Surgery: A Systematic Review and Network Meta-Analysis

Wang

Hao

et al. 2022

Surg Innov

View full text Add to dashboard Cite

Objective To identify superior pain-control procedures for postoperative patients who undergo cardiac surgeries. Methods Literature searches were conducted in globally recognized databases, including MEDLINE, EMBASE and Cochrane Central, to identify randomized controlled trials (RCTs) investigating pain-control procedures after cardiac surgeries. The parameters evaluating analgesic efficacy and postoperative recovery, namely, the pain score and ICU stay, were quantitatively pooled and estimated using Bayesian methods. The values of the surface under the cumulative ranking (SUCRA) probabilities regarding each parameter were calculated to enable the ranking of various pain-control procedures. Node-splitting analysis was performed to test the inconsistency of the main results, and the publication bias was assessed by examining the funnel-plot symmetry. Results After a detailed review, 13 RCTs containing 7 different procedures were included in the network meta-analysis. After pooling the results together, an erector spinae plane block (ESPB) and a local parasternal block (LPB) plus target-controlled infusion (TCI) presented the best analgesic effects for reducing pain at rest (SUCRA, .47) and during movement (SUCRA, .52), respectively, while the former also achieved the shortest ICU stay (SUCRA, .48). Moreover, the funnel-plot symmetries showed no inconsistencies or obvious publication bias in the current study. Conclusions The current evidence indicates that ESPB is a potential superior analgesic strategy for post-cardiac surgery patients. To verify this conclusion further, it is imperative to obtain more high-quality evidence and conduct relevant investigations in the future.

show abstract

“…56 Another RCT on the same topic failed to evaluate the pain-control efficacy because of the increased number of wound infections. 58…”

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Evaluation of Different Pain-Control Procedures for Post-cardiac Surgery: A Systematic Review and Network Meta-Analysis

Wang

Hao

et al. 2022

Surg Innov

View full text Add to dashboard Cite

show abstract

“…Importantly, local anesthetic-induced reductions in leukocyte activation do not seem to be offset by clinically relevant reductions in microbicidal capacity [44,45]. However, two reports caution that local anesthetics may increase the risk of preexisting bacterial infections [45,46]. These studies forecast a broader role for local anesthetics in perioperative management and stimulate interest to define their impact on the incidence of postoperative outcome -short and long-term -for various inflammatory disease states.…”

Section: Local Anestheticsmentioning

confidence: 99%

Anesthesia drugs, immunity, and long-term outcome

Homburger

Meiler

2006

Current Opinion in Anaesthesiology

View full text Add to dashboard Cite

show abstract

“…Da Lokalanästhetika die Leukozytenfunktion beeinträchtigen,wäre es denkbar,dass sie die Infektionsanfälligkeit erhöhen [18]. In der Literatur existieren derzeit 2 Studien,die diese Befürchtungen bestätigen.…”

Section: Lokalanästhetika Und Infektionsrisikounclassified

?Alternative? effects of local anesthetic agents

et al. 2004

View full text Add to dashboard Cite

The following article summarizes different aspects of local anesthetic effects that cannot be explained purely by a sodium channel blockade. Particularly remarkable is hereby their antiinflammatory activity, e.g. the inhibition of pathological changes such as excessive stimulation of the inflammatory system, without compromising the host defense system. In contrast to other immunosuppressive drugs commonly used for treating such conditions, local anesthetics look promising for the future as a new therapeutic option. Besides general anesthetic activity, local anesthetics exert cerebroprotective effects and are furthermore, in consideration of their cardiovascular stability, of interest during neuroanesthetic procedures. In addition, local anesthetics are known for their potency to minimize bronchial hyperreactivity, although details of the underlying mechanisms are not yet elucidated. These effects of local anesthetics may represent interesting prospects for which their relevance has to be determined.

show abstract

Caution in the Use of Lidocaine Infusion in the Surgical Patient

Cited by 3 publications

References 5 publications

Evaluation of Different Pain-Control Procedures for Post-cardiac Surgery: A Systematic Review and Network Meta-Analysis

Evaluation of Different Pain-Control Procedures for Post-cardiac Surgery: A Systematic Review and Network Meta-Analysis

Anesthesia drugs, immunity, and long-term outcome

?Alternative? effects of local anesthetic agents

Contact Info

Product

Resources

About