Caval Interruption for Prevention of Pulmonary Embolism

Mobin-Uddin, Kazi; McLean, Robert; Bolooki, Hooshang; Jude, James R.

doi:10.1001/archsurg.1969.01340180035006

Cited by 125 publications

(31 citation statements)

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“…Modern filters 1,2 have made steady improvements in design since their inception with the Mobin Uddin filter (66% IVC occlusion). 19,20 Of the filtration devices currently in use, the Greenfield filter continues to be among the most common and, arguably, has the best safety profile. The Greenfield stainless steel filter was introduced in 1994 and approved by the FDA in 1995.…”

Section: Discussionmentioning

confidence: 99%

Prospective randomized study comparing the clinical outcomes between inferior vena cava Greenfield and TrapEase filters

Usoh

Hingorani

Ascher

et al. 2010

Journal of Vascular Surgery

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Section: Discussionmentioning

confidence: 99%

Prospective randomized study comparing the clinical outcomes between inferior vena cava Greenfield and TrapEase filters

Usoh

Hingorani

Ascher

et al. 2010

Journal of Vascular Surgery

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“…12 In patients for whom anticoagulation is ineffective or contraindicated, a mechanical filter to trap emboli can be placed percutaneously in the inferior vena cava (IVC). 12 The first IVC filters were designed to mitigate the risks associated with ligation or plication of the vena cava, 28 but were subject to obstruction 8 and migration. 29 One design hypothesis is that filters should trap large thromboemboli (which can then undergo lysis by flowing blood), but pass small emboli that can be trapped and lysed in the lungs without serious patient harm.…”

Section: Introductionmentioning

confidence: 99%

Effects of Thrombosed Vena Cava Filters on Blood Flow: Flow Visualization and Numerical Modeling

et al. 2008

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Inferior vena cava (IVC) filters are used to prevent pulmonary embolism (PE) in patients with deep vein thrombosis for whom anticoagulation is contraindicated. IVC filters have been shown to be effective in trapping embolized clots and preventing PE; however, among the commercially available designs, the optimal balance of clot capture efficiency, clot dissolution, and prevention of to vena cava occlusion is unknown. Clot capture efficiency has been quantified in numerous in vitro studies, in which model clots are released into a mock circulation system, with the relative capture efficiency of various IVC filters analyzed statistically. In general, two-stage filters have been found to be more efficient than one-stage filters. However, other factors may play a role in the ultimate dissolution of clots and in the overall effect of the resulting blood flow on caval vasculature. Clot dissolution has been shown to increase with increasing wall shear stress, while low and oscillating wall shear stresses are known to have a deleterious effect on vessel walls, causing intimal hyperplasia. This paper describes the effect of IVC filters on blood flow, velocity patterns, and wall shear stress by flow visualization and computational fluid dynamics.

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“…The Mobin-Udin filter was the first IVC filter to be used [12]. It was developed in the 1960’s and was constructed like an inverted umbrella, made of stainless steel covered with a silastic coating.…”

Section: Discussionmentioning

confidence: 99%