Cavernous Hemangioma of the Liver: Ultrasonography, Arteriography, and Computed Tomography

Freeny, Patrick C.; Vimont, T.; Barnett, Donald C.

doi:10.1148/132.1.143

Cited by 93 publications

(16 citation statements)

References 5 publications

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“…It has been suggested that if a lesion is ultrasonically demonstrated to be cystic, diagnosis of a benign cystic lesion can generally be made and no further procedures need to be performed. 36 However, we as well as others3' have seen cavitary metastatic tumors in the liver simulating hepatic cysts on ultrasound studies. Aspiration of an echinococcus cyst should be contraindicated for fear of potential anaphylactic shock.…”

Section: Discussionsupporting

confidence: 48%

Diagnosis of primary hepatic neoplasms by fine‐needle aspiration cytology

Suen

1986

Diagnostic Cytopathology

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This article describes the cytologic features of various primary hepatic neoplasms as seen in fine-needle aspirates. Hepatocellular carcinoma can be differentiated from metastatic carcinoma by its tendency to recapitulate the characteristics of normal hepatocytes, namely, resemblance of the neoplastic cells to liver cells, growth in trabeculae, and bile production. Fibrolamellar hepatocellular carcinoma is characterized by larger, polygonal tumor cells with clearly defined cell outline, deeply eosinophilic granular cytoplasm, and extremely large solitary nucleoli. Lamellae of fibrocytes are seen dividing the tumor cells into small groups. Hepatocellular adenoma and focal nodular hyperplasia exhibit cells that are benign-appearing or minimally atypical. Cholangiocarcinoma is an adenocarcinoma and cannot be differentiated from metastatic adenocarcinoma on purely morphologic grounds. Primary hepatic sarcoma is exceptionally rare and shows malignant spindle cells. Some inflammatory conditions such as abscess, cysts, and tuberculoma often present as space-occupying lesions and should be included in the differential diagnosis of hepatic neoplasm.

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Section: Discussionsupporting

confidence: 48%

Diagnosis of primary hepatic neoplasms by fine‐needle aspiration cytology

Suen

1986

Diagnostic Cytopathology

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“…The results of many studies (1)(2)(3)(4)(5)(6)(7)(8) have documented the ultrasonographic (US) appearance of hepatic hemangiomas. The typical appearance is that of a hyperechoic, well-defined lesion with or without small central regions of decreased echogenicity.…”

Section: Discussionmentioning

confidence: 99%

Follow-up of Patients at Low Risk for Hepatic Malignancy with a Characteristic Hemangioma at US

Leifer

Middleton²,

Teefey³

et al. 2000

Radiology

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“…1 Their differentiation from malignant liver tumors is important because hepatic hemangiomas usually require no treatment. 2 The utility of enhanced computed tomography (CT) and gadolinium-diethylenetriaminepentaacetic acid (Gd-DTPA)-enhanced magnetic resonance (MR) imaging has been reported for the diagnosis of hepatic hemangiomas and their differentiation from malignant liver tumors. [3][4][5][6][7][8][9] The most common features of hepatic hemangiomas on enhanced CT and Gd-DTPA-enhanced MR imaging are peripheral or central nodular enhancement during the arterial phase, fill-in enhancement during the portal venous phase, and prolonged enhancement during the late phase.…”

Section: Introductionmentioning

confidence: 99%

Hepatic Hemangiomas: Factors Associated with Pseudo Washout Sign on Gd-EOB-DTPA-enhanced MR Imaging

et al. 2016

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Purpose: Our study aim was to clarify the characteristics of hemangiomas with pseudo washout sign (PWS) by comparing their features with those of hemangiomas without PWS on gadolinium-ethoxybenzyl-diethylenetriaminepentaacetic acid (Gd-EOB-DTPA)-enhanced magnetic resonance (MR) imaging.Methods: We evaluated the features of hemangiomas on Gd-EOB-DTPA-enhanced MR imaging of 70 hepatic hemangiomas in 31 patients, investigating the presence of peripheral or central nodular enhancement, diffuse enhancement, and arterioportal shunt during the arterial phase, fill-in enhancement during the portal venous phase, and PWS, which is low signal intensity during the late phase. We visually assessed the intensity of contrast enhancement of the lesion during the arterial, portal venous, late, and hepatobiliary phases using a 4-grade scale and used the Fisher exact and Mann-Whitney U tests to compare hemangiomas with and without PWS.Results: We observed PWS in 33 (47%) of 70 hemangiomas, which were significantly smaller than the hemangiomas without PWS (17.4 mm « 20.3 versus 30.1 mm « 28.5; P = 0.005); more frequent diffuse enhancement in hemangiomas with PWS than those without (21.2% versus 2.7%; P = 0.026); and no significant differences in nodular enhancement (P = 0.231), arterioportal shunt (P = 0.403), or fill-in enhancement (P = 0.357) between hemangiomas with and without PWS. Visually determined grades of tumor contrast enhancement were significantly lower in hemangiomas with PWS during the portal venous (P = 0.007) and late (P < 0.001) phases.Conclusions: Small hemangiomas tend to decrease in signal intensity during the portal venous phase and show PWS during the late phase.

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Cavernous Hemangioma of the Liver: Ultrasonography, Arteriography, and Computed Tomography

Cited by 93 publications

References 5 publications

Diagnosis of primary hepatic neoplasms by fine‐needle aspiration cytology

Diagnosis of primary hepatic neoplasms by fine‐needle aspiration cytology

Follow-up of Patients at Low Risk for Hepatic Malignancy with a Characteristic Hemangioma at US

Hepatic Hemangiomas: Factors Associated with Pseudo Washout Sign on Gd-EOB-DTPA-enhanced MR Imaging

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