2020
DOI: 10.7860/jcdr/2020/44615.14007
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Cavernous Sinus Metastasis from Carcinoma of Buccal Mucosa- A Rare Case Report and Review of Literature

Abstract: Distant metastasis from Head and Neck Squamous Cell Carcinomas (HNSCC) is uncommon, Cavernous Sinus (CS) metastasis being very rare. Infrequent presentation and misdiagnosis makes it a difficult entity to identify and treat. Hereby, Authors present a rare case of 47 year old male of CS metastasis from postoperative carcinoma of buccal mucosa. The patient was a histopathologically proven case of poorly differentiated Squamous Cell Carcinoma (SCC) of left buccal mucosa for which he underwent definitive surgery. … Show more

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“…There is an emerging trend of HPV-related OSCC without active HPV infection. HPV-related OSCC exhibits a propensity for RM to unusual sites, especially to the brain, dura mater, and bone; however, a contradictory view has also been reported [4][5][6][7]. The involvement of CS has a typical presentation of those chiefly related to cranial nerves III, IV, ophthalmic branch of V, VI involvement [7].…”
Section: Discussionmentioning
confidence: 99%
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“…There is an emerging trend of HPV-related OSCC without active HPV infection. HPV-related OSCC exhibits a propensity for RM to unusual sites, especially to the brain, dura mater, and bone; however, a contradictory view has also been reported [4][5][6][7]. The involvement of CS has a typical presentation of those chiefly related to cranial nerves III, IV, ophthalmic branch of V, VI involvement [7].…”
Section: Discussionmentioning
confidence: 99%
“…The role of stereotactic radiosurgery in treating brain metastasis is appealing lesions located in eloquent areas measuring < 2.5 cms lacking any considerable mass effect [ 1 ]. Gamma knife radiosurgery is an emerging concept in the surgical management of the symptomatic disease and has demonstrated reduction of the radiotherapy dose, enhanced tissue sparing effect, and thereby minimizing the toxicity [ 5 ].…”
Section: Discussionmentioning
confidence: 99%