Phys. Chem. Chem. Phys.
 2022
DOI: 10.1039/d1cp04460e
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Cavity-based free energy analysis of osmolyte effects on protein denaturation

Michael Heying
1
,
Kevin W. Lam
2
,
Abigail D. Richardson
3
et al.

Abstract: Experimental measurements of the thermal effects of the same osmolytes on two different globular proteins, C-reactive protein (CRP) and tumor necrosis factor alpha (TNFα), have shown that quantifying the change...

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