CBr₄: A Useful and Efficient Catalyst for One‐Pot Synthesis of 4‐Substituted‐1,4,5,6,7,8‐Hexahydroquinolin‐5‐ones Via Hantzsch Reaction

Abstract

A carbon tetrabromide (CBr 4 ) catalyzed one-pot synthesis of 4-substituted-1,4,5,6,7,8-hexahydroquinolin-5-one derivatives via a Hantzsch reaction under mild conditions was described.

Visible light-triggered synthesis of oxime ethers using tetrabromomethane as a mediator

“…The tribromomethyl radical then functions either as a hydrogen atom acceptor or as an electron acceptor for a series of substrates to chemoselectively and regioselectively induce cross-dehydrogenative coupling reactions. 11 Recently, pioneering work investigating CBr 4 mediated C–H functionalization for constructing C–X (X = C, N, O, etc. ) bonds has been reported.…”

Four-Component Fusion Protocol with NiO/ZrO2 as a Robust Recyclable Catalyst for Novel 1,4-Dihydropyridines

“…Due to the vast biological and synthetic importance of 1,4-DHP derivatives, several protocols have been reported via a one-pot strategy and employing different catalysts like nano-tungsten trioxide-supported sulfonic acid (n-WSA), 24 sulfated boric acid nanoparticles, 25 chitosan-supported copper(II) sulfate, 26 Fe 3 O 4 @SiO 2 @Si-(CH 2 ) 3 @melamine-picolineimine@SO 3 H, 27 sulfated polyborate, 28 Fe 3 O 4 /KCC-1/BPAT, 29 chitosan-supported vanadium oxo, 30 magnetic guanidinylated chitosan, 31 nano-ZrO 2 -SO 3 H (n-ZrSA), 32 Gd(OTf) 3 , 33 nicotinic acid, 34 γ-Fe 2 O 3 /Cu@cellulose, 35 SBA-15@AMPD-Co, 36 sulfamic acid, 19 Fe 3 O 4 @D-NH-(CH 2 ) 4 -SO 3 H, 37 Cu-adenine@boehmite, 38 hydromagnesite, 39 Cu(OTf) 2 , 40 ascorbic acid, 41 NS-C 4 (DABCO-SO 3 H) 2 ·4Cl, 42 CBr 4 , 43 and aminated CNTs. 14 Many of these methods either suffer from usage of reflux conditions, lower yields, or long reaction times.…”