cc-motif-chemokine-ligand-21-immune-targeting-head-and-neck-oncology-and-future-prospective/#

Abstract

Investigations in immunomodulating therapies for cancer treatment over the past 20 years have flourished. Given the complex tumor microenvironment and differential signaling pathways a wide variety of potential targeting mechanisms have come to attention. Herein we review the immunomodulating potential of Chemokine 21 in pre-clinical and clinical studies, as well as examine the novel multi-faceted immune-based treatments in advanced head and neck cancer.