2023
DOI: 10.1002/eji.202250333
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CD1a and bound lipids drive T‐cell responses in human skin disease

Abstract: In addition to serving as the main physical barrier with the outside world, human skin is abundantly infiltrated with resident αβ T cells that respond differently to self, infectious, microbiome and noxious stimuli.  To study skin T cells during infection and inflammation, experimental biologists track T cell surface phenotypes and effector functions, which are often interpreted with the untested assumption that MHC proteins and peptide antigens drive measured responses.  However, a broader perspective is that… Show more

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Cited by 3 publications
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