Abstract:The adaptive immune response to severe acute respiratory coronavirus 2 (SARS-CoV-2) is important for vaccine development and coronavirus disease 2019 (COVID-19) recovery. Men and cancer patients have been reported to be at higher risks of contracting the virus and developing severe COVID-19. Prostate cancer (PCa) may be associated with both of these risks. We show that CD4+ T cells of SARS-CoV-2-unexposed patients with hormone-refractory (HR) metastatic PCa have substantially decreased CD4+ T cell immune respo… Show more
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